Design, Synthesis, and Evaluation of Novel Metabotropic Glutamate Subtype-2 (mGlu2) Receptor Positive Allosteric Modulators (PAMs) in Rodent Models of Drug Dependence

被引:0
作者
Cosford, N. [1 ,2 ]
Dhanya, R. [1 ,2 ]
Sidique, S. [1 ,2 ]
Sheffler, D. [3 ]
Nickols, H. [3 ]
Herath, A. [1 ,2 ]
Yang, L. [1 ,2 ]
Dahl, R. [1 ,2 ]
Ardecky, R. [1 ,2 ]
Semenova, S. [4 ]
Conn, P. J. [3 ]
Markou, A. [4 ]
机构
[1] Sanford Burnham Med Res Inst, Apoptosis & Cell Death Res Program, La Jolla, CA 92037 USA
[2] Sanford Burnham Med Res Inst, Conrad Prebys Ctr Chem Genom, La Jolla, CA 92037 USA
[3] Vanderbilt Univ, Med Ctr, Vanderbilt Ctr Neurosci Drug Discovery, Nashville, TN 37232 USA
[4] Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USA
关键词
RATS;
D O I
暂无
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
33
引用
收藏
页码:12 / 12
页数:1
相关论文
共 3 条
  • [1] Design and Synthesis of an Orally Active Metabotropic Glutamate Receptor Subtype-2 (mGluR2) Positive Allosteric Modulator (PAM) That Decreases Cocaine Self-Administration in Rats
    Dhanya, Raveendra-Panickai
    Sidique, Shyama
    Sheffler, Douglas J.
    Nickols, Hilary Highfield
    Herath, Ananda
    Yang, Li
    Dahl, Russell
    Ardecky, Robert
    Semenova, Svetlana
    Markou, Athina
    Conn, P. Jeffrey
    Cosford, Nicholas D. P.
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2011, 54 (01) : 342 - 353
  • [2] The mGluR2 Positive Allosteric Modulator BINA Decreases Cocaine Self-Administration and Cue-Induced Cocaine-Seeking and Counteracts Cocaine-Induced Enhancement of Brain Reward Function in Rats
    Jin, Xinchun
    Semenova, Svetlana
    Yang, Li
    Ardecky, Robert
    Sheffler, Douglas J.
    Dahl, Russell
    Conn, P. Jeffrey
    Cosford, Nicholas D. P.
    Markou, Athina
    [J]. NEUROPSYCHOPHARMACOLOGY, 2010, 35 (10) : 2021 - 2036
  • [3] Sheffler D, 2011, CHEM NEUROS IN PRESS