Cyano-bridged coordination polymer nanoparticles with high nuclear relaxivity:: toward new contrast agents for MRI

被引:63
作者
Guari, Yannick [1 ]
Larionova, Joulia [1 ]
Corti, Maurizio [4 ]
Lascialfari, Alessandro [2 ,3 ,4 ]
Marinone, Massimo [2 ,3 ]
Poletti, Giulio [2 ,3 ]
Molvinger, Karine [5 ]
Guerin, Christian [1 ]
机构
[1] Univ Montpellier 2, Inst Charles Gerhardt Montpellier, UMR 5253, F-34095 Montpellier 5, France
[2] Univ Milan, Ist Fisiol Gen & Chim Biol, I-20134 Milan, Italy
[3] CNR, INFM, S3 NRC, I-41100 Modena, Italy
[4] Univ Pavia, Dipartimento Fis A Volta, CNR, INFM, I-27100 Pavia, Italy
[5] Ecole Natl Super Chim Montpellier, Inst Charles Gerhardt Montpellier, UMR 5253, F-34296 Montpellier 5, France
关键词
D O I
10.1039/b808221a
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
New water-soluble paramagnetic Gd-containing cyano-bridged metallic coordination polymer nanoparticles with a chitosan shell show high nuclear relaxivity in acidic water which is up to six times higher than that of the actually used Gd-chelates.
引用
收藏
页码:3658 / 3660
页数:3
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