H/D isotope substitution effect on the structural and thermodynamic parameters of intermolecular interaction in methanol at 278-318 K

The effect of H/D isotope substitution in methanol molecules on the geometrical parameters of the latter and the energetics of particle interactions is discussed in terms of scale particle theory and a model using internal pressure as a measure of nonspecific interactions in liquids. Deuteration leads to reduced space occupied by a molecule irt the structural matrix of methanol. It is established that isotopic substitution differentiates the distribution of specific and van der Waals interactions. The Sonnei are strengthened and the latter weakened,when protium is substituted by deuterium in a group forming hydrogen bonds, and the case is opposite when deuterium is replaced in the methyl radical of methanol.