Acute kidney injury in congenital heart disease

被引:22
作者
Gist, Katja M. [1 ]
Kwiatkowski, David M. [2 ]
Cooper, David S. [3 ]
机构
[1] Univ Colorado, Inst Heart, Childrens Hosp Colorado, Aurora, CO USA
[2] Stanford Univ, Div Cardiol, Lucile Packard Childrens Hosp, Palo Alto, CA 94304 USA
[3] Univ Cincinnati, Coll Med, Cincinnati Childrens Hosp Med Ctr, Ctr Acute Care Nephrol,Heart Inst, 3333 Burnet Ave,MLC 2003, Cincinnati, OH 45229 USA
关键词
congenital heart disease; acute kidney injury; cardiorenal syndrome; fluid overload; long-term outcomes; ACUTE-RENAL-FAILURE; GELATINASE-ASSOCIATED LIPOCALIN; CARDIAC-SURGERY; FLUID OVERLOAD; CYSTATIN-C; SERUM CREATININE; RISK-FACTORS; LONG-TERM; PERITONEAL-DIALYSIS; POOR OUTCOMES;
D O I
10.1097/HCO.0000000000000473
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of reviewAcute kidney injury (AKI) is associated with significant morbidity and mortality in patients with congenital heart disease undergoing cardiac surgery or in pediatric patients with congestive heart failure.Recent findingsThis review describes the definition and various manifestations of AKI, the impact of biomarkers on the diagnosis of AKI, the importance of fluid overload as a consequence of AKI and its long-term impact.SummaryThere are novel biomarkers for AKI detection that should facilitate early recognition and intervention to prevent or attenuate the effects of AKI and fluid overload. Previous conventional wisdom that survivors of AKI fully recover renal function without subsequent consequences is flawed.
引用
收藏
页码:101 / 107
页数:7
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