Systemic Mastocytosis, Version 2.2019

被引：37

作者：

Gotlib, Jason ^{[3
]}

Gerds, Aaron T. ^{[1
,2
]}

Bose, Prithviraj ^{[4
]}

Castells, Mariana C. ^{[5
]}

Deininger, Michael W. ^{[6
]}

Gojo, Ivana ^{[7
]}

Gundabolu, Krishna ^{[8
]}

Hobbs, Gabriela ^{[9
]}

Jamieson, Catriona ^{[10
]}

McMahon, Brandon ^{[11
]}

Mohan, Sanjay R. ^{[12
]}

Oehler, Vivian ^{[13
]}

Oh, Stephen ^{[14
,15
]}

Padron, Eric ^{[16
]}

Pancari, Philip ^{[17
]}

Papadantonakis, Nikolaos ^{[18
]}

Pardanani, Animesh ^{[19
]}

Podoltsev, Nikolai ^{[20
]}

Rampal, Raajit ^{[21
]}

Ranheim, Erik ^{[22
]}

Rein, Lindsay ^{[23
]}

Snyder, David S. ^{[24
]}

Stein, Brady L. ^{[25
]}

Talpaz, Moshe ^{[26
]}

Thota, Swapna ^{[27
]}

Wadleigh, Martha ^{[5
]}

Walsh, Katherine ^{[28
,29
]}

Bergman, Mary Anne ^{[30
]}

Sundar, Hema ^{[30
]}

机构：

[1] Univ Hosp Seidman Canc Ctr, Case Comprehens Canc Ctr, Cleveland, OH USA

[2] Cleveland Clin, Taussig Canc Inst, Cleveland, OH 44106 USA

[3] Stanford Canc Inst, Stanford, CA USA

[4] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

[5] Dana Farber Brigham & Womens Canc Ctr, Boston, MA USA

[6] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT 84112 USA

[7] Sidney Kimmel Comprehens Canc Ctr Johns Hopkins, Baltimore, MD USA

[8] Fred & Pamela Buffett Canc Ctr, Omaha, NE USA

[9] Massachusetts Gen Hosp, Ctr Canc, Boston, MA 02114 USA

[10] Univ Calif San Diego, Moores Canc Ctr, San Diego, CA USA

[11] Univ Colorado, Ctr Canc, Boulder, CO 80309 USA

[12] Vanderbilt Ingram Canc Ctr, Nashville, TN USA

[13] Fred Hutchinson Canc Res Ctr, Seattle Canc Care Alliance, 1124 Columbia St, Seattle, WA 98104 USA

[14] Barnes Jewish Hosp, Siteman Canc Ctr, St Louis, MO 63110 USA

[15] Washington Univ, Sch Med, St Louis, MO 63130 USA

[16] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA

[17] Fox Chase Canc Ctr, 7701 Burholme Ave, Philadelphia, PA 19111 USA

[18] Univ Alabama Birmingham, Ctr Comprehens Canc, Birmingham, AL USA

[19] Mayo Clin, Ctr Canc, Rochester, MN USA

[20] Smilow Canc Hosp, Yale Canc Ctr, New Haven, CT USA

[21] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA

[22] Univ Wisconsin, Carbone Canc Ctr, Madison, WI 53706 USA

[23] Duke Canc Inst, Durham, NC USA

[24] City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USA

[25] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA

[26] Univ Michigan, Rogel Canc Ctr, Ann Arbor, MI 48109 USA

[27] Roswell Pk Comprehens Canc Ctr, Buffalo, NY USA

[28] Ohio State Univ, Ctr Comprehens Canc, James Canc Hosp, Columbus, OH 43210 USA

[29] Solove Res Inst, Columbus, OH USA

[30] Discuss Sect Writing Comm, Columbus, OH USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2018年 / 16卷 / 12期

关键词：

MAST-CELL ACTIVATION; KIT D816V MUTATION; HYMENOPTERA VENOM ALLERGY; BASAL SERUM TRYPTASE; INTERFERON-ALPHA; SPANISH NETWORK; C-KIT; RISK-FACTORS; PHASE-II; CLINICOPATHOLOGICAL FEATURES;

D O I：

10.6004/jnccn.2018.0088

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Mastocytosis is a group of heterogeneous disorders resulting from the clonal proliferation of abnormal mast cells and their accumulation in the skin and/or in various extracutaneous organs. Systemic mastocytosis is the most common form of mastocytosis diagnosed in adults, characterized by mast cell infiltration of one or more extracutaneous organs (with or without skin involvement). The identification of KIT D816V mutation and the emergence of novel targeted therapies have significantly improved the diagnosis and treatment of systemic mastocytosis. However, certain aspects of clinical care, particularly the diagnosis, assessment, and management of mediator-related symptoms continue to present challenges. This manuscript discusses the recommendations outlined in the NCCN Guidelines for the diagnosis and management of patients with systemic mastocytosis.

引用

页码：1500 / 1537

页数：38

共 157 条

[1] Disease spectrum in patients with elevated serum tryptase levels
Aberer, Elisabeth
Savic, Sandra
Bretterklieber, Agnes
Reiter, Harald
Berghold, Andrea
Aberer, Werner
[J]. AUSTRALASIAN JOURNAL OF DERMATOLOGY, 2015, 56 (01) : 7 - 13
[2] A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinib
Akin, C
Fumo, G
Yavuz, AS
Lipsky, PE
Neckers, L
Metcalfe, DD
[J]. BLOOD, 2004, 103 (08) : 3222 - 3225
[3] Effects of tyrosine kinase inhibitor STI571 on human mast cells bearing wild-type or mutated c-kit
Akin, C
Brockow, K
D'Ambrosio, C
Kirshenbaum, AS
Ma, YS
Longley, BJ
Metcalfe, DD
[J]. EXPERIMENTAL HEMATOLOGY, 2003, 31 (08) : 686 - 692
[4] Demonstration of an aberrant mast-cell population with clonal markers in a subset of patients with "idiopathic" anaphylaxis
Akin, Cem
Scott, Linda M.
Kocabas, Can N.
Kushnir-Sukhov, Nataliya
Brittain, Erica
Noel, Pierre
Metcalfe, Dean D.
[J]. BLOOD, 2007, 110 (07) : 2331 - 2333
[5] Mast cell activation syndromes
Akin, Cem
[J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2017, 140 (02) : 349 - 355
[6] Imatinib in systemic mastocytosis: a phase IV clinical trial in patients lacking exon 17 KIT mutations and review of the literature
Alvarez-Twose, Ivan
Matito, Almudena
Mario Morgado, Jose
Sanchez-Munoz, Laura
Jara-Acevedo, Maria
Garcia-Montero, Andres
Mayado, Andrea
Caldas, Carolina
Teodosio, Cristina
Ignacio Munoz-Gonzalez, Javier
Mollejo, Manuela
Escribano, Luis
Orfao, Alberto
[J]. ONCOTARGET, 2017, 8 (40) : 68950 - 68963
[7] Clinical, immunophenotypic, and molecular characteristics of well-differentiated systemic mastocytosis
Alvarez-Twose, Ivan
Jara-Acevedo, Maria
Mario Morgado, Jose
Garcia-Montero, Andres
Sanchez-Munoz, Laura
Teodosio, Cristina
Matito, Almudena
Mayado, Andrea
Caldas, Carolina
Mollejo, Manuela
Orfao, Alberto
Escribano, Luis
[J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2016, 137 (01) : 168 - +
[8] Nonaggressive systemic mastocytosis (SM) without skin lesions associated with insect-induced anaphylaxis shows unique features versus other indolent SM
Alvarez-Twose, Ivan
Zanotti, Roberta
Gonzalez-de-Olano, David
Bonadonna, Patrizia
Vega, Arantza
Matito, Almudena
Sanchez-Munoz, Laura
Mario Morgado, Jose
Perbellini, Omar
Garcia-Montero, Andres
De Matteis, Giovanna
Teodosio, Cristina
Rossini, Maurizio
Jara-Acevedo, Maria
Schena, Donatella
Mayado, Andrea
Zamo, Alberto
Mollejo, Manuela
Sanchez-Lopez, Paula
Cabanes, Nieves
Orfao, Alberto
Escribano, Luis
[J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 133 (02) : 520 - +
[9] Systemic mastocytosis as a risk factor for severe Hymenoptera sting-induced anaphylaxis
Alvarez-Twose, Ivan
Bonadonna, Patrizia
Matito, Almudena
Zanotti, Roberta
Gonzalez-de-Olano, David
Sanchez-Munoz, Laura
Mario Morgado, Jose
Orfao, Alberto
Escribano, Luis
[J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2013, 131 (02) : 614 - 615
[10] [Anonymous], 2017, WHO CLASSIFICATION T

← 1 2 3 4 5 6 7 8 9 10 →