Dose adaptation of the drugs used for hematopoietic stem-cell transplantation in patients with comorbidity: Obesity, chronic renal disease or hepatopathy: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)

被引：7

作者：

Simon, Nicolas ^{[1
,2
]}

Coiteux, Valerie ^{[3
]}

Bruno, Benedicte ^{[4
]}

Taque, Sophie ^{[5
]}

Charbonnier, Amandine ^{[6
]}

Souchet, Laetitia ^{[7
]}

Vincent, Laure ^{[8
]}

Yakoub-Agha, Ibrahim ^{[9
]}

Chalandon, Yves ^{[10
,11
]}

机构：

[1] Univ Lille, GRITA, EA 7365, F-59000 Lille, France

[2] CHU Lille, Inst Pharm, F-59000 Lille, France

[3] CHU Lille, Serv Malad Sang, F-59000 Lille, France

[4] CHU Lille, Serv Hematol Pediat, F-59000 Lille, France

[5] CHU Anne de Bretagne, Serv Hematooncol Pediat, 2 Rue Henri Le Guilloux, F-35033 Rennes 9, France

[6] CHU Amiens, Serv Hematol Clin & Therapie Cellulaire, F-80054 Amiens 1, France

[7] Grp Hosp Pitie Salpetriere, Serv Hematol Clin, 47-83 Blvd Hop, F-75013 Paris, France

[8] CHU Montpellier, Dept Hematol Clin, 191 Ave Doyen Gaston Giraud, F-34295 Montpellier, France

[9] Univ Lille 2, CHU Lille, LIRIC Inserm U995, F-59000 Lille, France

[10] Univ Geneva, Hop Univ Geneve, Serv Hematol, 4 Rue Gabrielle Perret Gentil, CH-1205 Geneva, Switzerland

[11] Univ Geneva, Fac Med, Serv Hematol, 4 Rue Gabrielle Perret Gentil, CH-1205 Geneva, Switzerland

来源：

BULLETIN DU CANCER | 2017年 / 104卷 / 12期

关键词：

Allogeneic stem cell transplantation; Chronic kidney disease; Comorbidity; Hepatopathy; Obesity; GLOMERULAR-FILTRATION-RATE; AMERICAN SOCIETY; POPULATION PHARMACOKINETICS; CHEMOTHERAPY; BUSULFAN; RECOMMENDATIONS; CREATININE; REGIMEN; BLOOD; ADJUSTMENT;

D O I：

10.1016/j.bulcan.2017.07.010

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In September 2016 in Lille, France, the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC) organized the 7th Allogeneic Stem Cell Transplantation Clinical Practices Harmonization Workshop Series. Our work group focused on chemotherapy drug dose adaptation for hematopoietic stem cell transplantation patients presenting a comorbidity. The purpose of this workshop was to provide recommendations on chemotherapy drug dose adaptation for patient populations receiving hematopoietic stem cell transplantation who also had the following comorbidities: obesity, chronic kidney disease and hepatopathy.

引用

页码：S99 / S105

页数：7

共 27 条

[1]

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[2] Pharmacokinetics of cyclophosphamide (CP) and 4-OH-CP/aldophosphamide in systemic vasculitis [J].