Immune dysfunction leads to mortality and organ injury in patients with COVID-19 in China: insights from ERS-COVID-19 study

被引：65

作者：

Li, Dongze ^{[1
,2
]}

Chen, You ^{[3
]}

Liu, Hong ^{[1
,2
]}

Jia, Yu ^{[1
,2
]}

Li, Fanghui ^{[1
,2
]}

Wang, Wei ^{[1
,2
]}

Wu, Jiang ^{[1
,2
]}

Wan, Zhi ^{[1
,2
]}

Cao, Yu ^{[1
,2
]}

Zeng, Rui ^{[1
,2
,4
]}

机构：

[1] Sichuan Univ, Deep Underground Space Med Ctr, Dept Emergency Med,Disaster Med Ctr, West China Sch Nursing,West China Hosp, Chengdu, Peoples R China

[2] Sichuan Univ, Deep Underground Space Med Ctr, Lab Emergency Med,Disaster Med Ctr, West China Sch Nursing,West China Hosp, Chengdu, Peoples R China

[3] Xinjiang Med Univ, Dept Cardiol, Affiliated Hosp 1, Urumqi, Peoples R China

[4] Sichuan Univ, West China Hosp, Dept Cardiol, Chengdu, Peoples R China

来源：

SIGNAL TRANSDUCTION AND TARGETED THERAPY | 2020年 / 5卷 / 01期

关键词：

COVID-19; Immune dysfunction; Mortality; Organ injury;

D O I：

10.1038/s41392-020-0163-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页数：3

共 4 条

[1]

Huang CL, 2020, LANCET, V395, P497, DOI [10.1016/S0140-6736(20)30211-7, 10.1016/S0140-6736(20)30183-5]

[2]

National Health Commission of the People's Republic of China, DIAGN TREATM SCHEM N

[3] Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China [J].

Qin, Chuan ;

Zhou, Luoqi ;

Hu, Ziwei ;

Zhang, Shuoqi ;

Yang, Sheng ;

Tao, Yu ;

Xie, Cuihong ;

Ma, Ke ;

Shang, Ke ;

Wang, Wei ;

Tian, Dai-Shi .

CLINICAL INFECTIOUS DISEASES, 2020, 71 (15) :762-768

[4] Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients [J].

Zhou, Yonggang ;

Fu, Binqing ;

Zheng, Xiaohu ;

Wang, Dongsheng ;

Zhao, Changcheng ;

Qi, Yingjie ;

Sun, Rui ;

Tian, Zhigang ;

Xu, Xiaoling ;

Wei, Haiming .

NATIONAL SCIENCE REVIEW, 2020, 7 (06) :998-1002

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