Preparation of alkylidene indane and related scaffolds and their further elaboration to novel chemotypes

被引：36

作者：

Kesavan, Sarathy ^{[1
]}

Panek, James S. ^{[1
]}

Porco, John A., Jr. ^{[1
]}

机构：

[1] Boston Univ, Ctr Chem Methodol & Library Dev, Dept Chem, Boston, MA 02215 USA

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 25期

关键词：

D O I：

10.1021/ol7023778

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Alkylidene indane and ring-expanded scaffolds have been prepared using an enantioselective crotylation/Heck cyclization sequence. Further diversification using consecutive cyclopropanation-Cope rearrangement affords novel chemotypes including spiroindane frameworks.

引用

页码：5203 / 5206

页数：4

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