Topical treatments for erythromelalgia

被引：1

作者：

Raef, Haya S. ^{[1
]}

Williams, Marta ^{[2
]}

Fedeles, Flavia ^{[2
,3
]}

机构：

[1] Tufts Univ, Sch Med, Boston, MA 02111 USA

[2] Harvard Med Sch, Boston, MA 02115 USA

[3] Massachusetts Gen Hosp, Dept Dermatol, 50 Staniford St,Suite 200, Boston, MA 02114 USA

来源：

DERMATOLOGIC THERAPY | 2022年 / 35卷 / 11期

关键词：

erythromelalgia; hyperanalgesia; pain; SCN9A; topical therapies; voltage-gated sodium channel; TARTRATE GEL 0.5-PERCENT; SEVERE FACIAL ERYTHEMA; DOXEPIN HYDROCHLORIDE; NEUROPATHIC PAIN; COMBINATION GEL; LIDOCAINE PATCH; DOUBLE-BLIND; CREAM; AMITRIPTYLINE; KETAMINE;

D O I：

10.1111/dth.15860

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Erythromelalgia is a rare neurovascular disease that causes episodes of pain, redness, and warmth in the extremities, and can be debilitating. Currently, there is no universally effective treatment for erythromelalgia. As the precise etiology of erythromelalgia remains obscure, presently available treatments are aimed at alleviating erythromelalgia's wide-ranging symptoms. In general, topical therapies for erythromelalgia are preferred for their more limited side effects and for those with contraindications to systemic therapies. This review will summarize the current topical therapies available to treat erythromelalgia and discuss emerging therapies based on our growing understanding of erythromelalgia pathophysiology.

引用

页数：5

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