A Review of Commercial Developments and Recent Laboratory Research of Dialyzers and Membranes for Hemodialysis Application

被引：64

作者：

Said, Noresah ^{[1
]}

Lau, Woei Jye ^{[1
]}

Ho, Yeek-Chia ^{[2
]}

Lim, Soo Kun ^{[3
]}

Abidin, Muhammad Nidzhom Zainol ^{[1
]}

Ismail, Ahmad Fauzi ^{[1
]}

机构：

[1] Univ Teknol Malaysia, Adv Membrane Technol Res Ctr AMTEC, Sch Chem & Energy Engn, Skudai 81310, Malaysia

[2] Univ Teknol PETRONAS, Inst Self Sustainable Bldg, Ctr Urban Resource Sustainabil, Dept Civil & Environm Engn, Seri Iskandar 32610, Perak, Malaysia

[3] Univ Malaya, Univ Malaya Primary Care Res Grp UMPCRG, Fac Med, Dept Primary Care Med, Kuala Lumpur 50603, Malaysia

来源：

MEMBRANES | 2021年 / 11卷 / 10期

关键词：

commercial dialyzer; dialysis; membrane; dialyzer design; hemodialysis; blood; MIXED-MATRIX MEMBRANES; NANOCOMPOSITE NANOFILTRATION-MEMBRANE; HIGH-PERFORMANCE MEMBRANE; HOLLOW-FIBER MEMBRANES; DIALYSIS MEMBRANE; UREMIC TOXINS; MASS-TRANSFER; POLYETHERSULFONE MEMBRANES; POLYMERIC MEMBRANES; MOLECULAR-WEIGHT;

D O I：

10.3390/membranes11100767

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Dialyzers have been commercially used for hemodialysis application since the 1950s, but progress in improving their efficiencies has never stopped over the decades. This article aims to provide an up-to-date review on the commercial developments and recent laboratory research of dialyzers for hemodialysis application and to discuss the technical aspects of dialyzer development, including hollow fiber membrane materials, dialyzer design, sterilization processes and flow simulation. The technical challenges of dialyzers are also highlighted in this review, which discusses the research areas that need to be prioritized to further improve the properties of dialyzers, such as flux, biocompatibility, flow distribution and urea clearance rate. We hope this review article can provide insights to researchers in developing/designing an ideal dialyzer that can bring the best hemodialysis treatment outcomes to kidney disease patients.</p>

引用

页数：38

共 145 条

[1]

A G, Int Res J Pharm, DOI DOI 10.7897/2230-8407.04505

[2] Development of biocompatible and safe polyethersulfone hemodialysis membrane incorporated with functionalized multi-walled carbon nanotubes [J].

Abidin, Muhammad Nidzhom Zainol ;

Goh, Pei Sean ;

Ismail, Ahmad Fauzi ;

Othman, Mohd Hafiz Dzarfan ;

Hasbullah, Hasrinah ;

Said, Noresah ;

Kadir, Siti Hamimah Sheikh Abdul ;

Kamal, Fatmawati ;

Abdullah, Mohd Sohaimi ;

Ng, Be Cheer .

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2017, 77 :572-582

[3] Antifouling polyethersulfone hemodialysis membranes incorporated with poly (citric acid) polymerized multi-walled carbon nanotubes [J].

Abidin, Muhammad Nidzhom Zainol ;

Goh, Pei Sean ;

Ismail, Ahmad Fauzi ;

Othman, Mohd Hafiz Dzarfan ;

Hasbullah, Hasrinah ;

Said, Noresah ;

Kadir, Siti Hamimah Sheikh Abdul ;

Kamal, Fatmawati ;

Abdullah, Mohd Sohaimi ;

Ng, Be Cheer .

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2016, 68 :540-550

[4]

Ahmad G., 2012, HAEM QUAL STAND, V12

[5] Surface characteristics and blood compatibility of PVDF/PMMA membranes [J].

Ai, Fei ;

Li, Hong ;

Wang, Quan ;

Yuan, Wang Zhang ;

Chen, Xiaoyong ;

Yang, Libin ;

Zhao, Junhong ;

Zhang, Yongming .

JOURNAL OF MATERIALS SCIENCE, 2012, 47 (12) :5030-5040

[6]

Allard B., 2013, PHARM HOSP CLIN, V48, P21, DOI DOI 10.1016/J.PHCLIN.2013.10.071

[7] Myoglobin clearance and removal during continuous venovenous hemofiltration [J].

Amyot, SL ;

Leblanc, M ;

Thibeault, Y ;

Geadah, D ;

Cardinal, J .

INTENSIVE CARE MEDICINE, 1999, 25 (10) :1169-1172

[8]

[Anonymous], 2010, COMPREHENSIVE MEMBRA, DOI [DOI 10.1016/B978-0-08-093250-7.00030-X, 10.1016/B978-0-08-093250-7.00030-X]

[9]

[Anonymous], 2013, CLIN UPD DIAL MEMBR

[10]

Azar AT, 2009, SAUDI J KIDNEY DIS T, V20, P1023

← 1 2 3 4 5 6 7 8 9 10 →