Synthesis of some new 2-(4-nitrobenzothiazol-2′-ylamino)-4-(2-chloro-4-trifluoromethylanilino)-6-(substituted thioureido)-1,3,5-triazines as antifungal agents

被引:14
作者
Sareen, Vineeta
Khatri, Vineeta
Garg, Urmila
Jain, Prakash
Sharma, Kanti [1 ]
机构
[1] SK Govt PG Coll, Dept Chem, Rajasthan 332001, India
[2] Univ Rajasthan, Dept Chem, Jaipur 302004, Rajasthan, India
关键词
2-(4-nitrobenzothiazol-2'-ylamino)-4,6-dichloro-1,3,5-triazine; 2-(4-nitrobenzothiazol-2'-ylamino)-4-(2-chloro-4-trifluoromethyl-anilino); -6-chloro-1,3,5-triazine; 2-(4-nitrobenzothiazol-2'-ylamino)-4-(2-chloro-4-trifluoromethylanilino)-6-(substituted; thioureido)-1,3,5-triazine; antimicrobial activity;
D O I
10.1080/10426500701544474
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Some new 2-(4-nitrobenzothiazol-2'-ylamino)-4-(2-chloro-4-trifluoro-methylanilino)-6-(substituted thioureido)-1,3,5-triazine 4 have been prepared by reacting 2,4,6-trichloro-1,3,5-triazine with nucleophilic reagents, 2-amino-4-nitrobenzothiazol 1,2-chloro-4-trifluorornethylaniline 2 and different substituted thioureas 3 to give the title compound. These compounds are evaluated for their antimicrobial activity. The structure of all of these compounds has been confirmed by IR, H-1 NMR, F-19 NMR, mass spectral data and elemental analysis.
引用
收藏
页码:2943 / 2948
页数:6
相关论文
共 4 条
[1]  
BRYANT MC, 1968, ANTIBIOTICS THEIR LA, V26
[2]  
DESAI PS, 1994, J INDIAN CHEM SOC, V71, P155
[3]  
Sareen V, 2005, INDIAN J HETEROCY CH, V15, P193
[4]  
Sareen V, 2006, INDIAN J CHEM B, V45, P1288