Biomaterials & scaffolds for tissue engineering

被引:2558
作者
O'Brien, Fergal J. [1 ,2 ]
机构
[1] Royal Coll Surgeons Ireland, Dept Anat, Dublin 2, Ireland
[2] Trinity Coll Dublin, Dept Mech Engn, Trinity Ctr Bioengn, Dublin 2, Ireland
基金
欧洲研究理事会; 爱尔兰科学基金会;
关键词
COLLAGEN-GAG SCAFFOLDS; INDUCED PHASE-SEPARATION; DELIVERY IN-VIVO; EXTRACELLULAR-MATRIX; ARTIFICIAL SKIN; GENE DELIVERY; PORE-SIZE; REGENERATIVE MEDICINE; MECHANICAL-PROPERTIES; COMPOSITE SCAFFOLDS;
D O I
10.1016/S1369-7021(11)70058-X
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Every day thousands of surgical procedures are performed to replace or repair tissue that has been damaged through disease or trauma. The developing field of tissue engineering (TE) aims to regenerate damaged tissues by combining cells from the body with highly porous scaffold biomaterials, which act as templates for tissue regeneration, to guide the growth of new tissue. This article describes the functional requirements, and types, of materials used in developing state of the art of scaffolds for tissue engineering applications. Furthermore, it describes the challenges and where future research and direction is required in this rapidly advancing field.
引用
收藏
页码:88 / 95
页数:8
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