Maternal arsenic exposure associated with low birth weight in Bangladesh

被引：88
作者：
Huyck, Karen L.
Kile, Molly L.
Mahiuddin, Golam
Quamruzzaman, Quazi
Rahman, Mahmuder
Breton, Carrie V.
Dobson, Christine B.
Frelich, Janna
Hoffman, Elaine
Yousuf, Jabed
Afroz, Sakila
Islam, Shofiqul
Christiani, David C.
机构：
[1] Harvard Univ, Sch Publ Hlth, Dept Environm Hlth, Boston, MA 02115 USA
[2] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
[3] Harvard Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA
[4] Dhaka Community Hosp, Dhaka, Bangladesh
来源：
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE | 2007年 / 49卷 / 10期
关键词：
D O I：
10.1097/JOM.0b013e3181566ba0
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Objective: To characterize the effects of maternal arsenic exposure on birth weight. Methods: Hair, toenail, and drinking water samples were collected from pregnant women (n = 52) at multiple time points during pregnancy and from their newborns after birth. Total arsenic was measured using inductively coupled plasma-mass spectrometry. The association between arsenic and birth weight was investigated using linear and logistic regression models. Results: Maternal hair arsenic measured early in pregnancy was associated with decreased birth weight (beta = - 193.5 +/- 90.0 g, P = 0.04). Maternal hair and drinking water arsenic levels measured at first prenatal visit were significantly correlated with newborn hair arsenic level (beta = 0.32, P = 0.04 and beta = 0.31, P = 0.04). Conclusions: Results suggest that maternal arsenic exposure early in pregnancy negatively affects newborn birth weight and that maternal hair provides the best integrated measure of arsenic exposure.
引用
收藏
页码：1097 / 1104
页数：8
相关论文
共 40 条
[1]   Arsenic in drinking water and pregnancy outcomes [J].
Ahmad, SA ;
Sayed, SU ;
Barua, S ;
Khan, MH ;
Jalil, A ;
Hadi, SA ;
Talukder, HK .
ENVIRONMENTAL HEALTH PERSPECTIVES, 2001, 109 (06) :629-631
[2]   Arsenic contamination in Bangladesh groundwater: a major environmental and social disaster [J].
Alam, MGM ;
Allinson, G ;
Stagnitti, F ;
Tanaka, A ;
Westbrooke, M .
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH, 2002, 12 (03) :236-253
[3]   Determination of the total arsenic concentration in human urine by inductively coupled plasma mass spectrometry: a comparison of the accuracy of three analytical methods [J].
Amarasiriwardena, CJ ;
Lupoli, N ;
Potula, V ;
Korrick, S ;
Hu, H .
ANALYST, 1998, 123 (03) :441-445
[4]   QUALITY OF COMMUNITY DRINKING-WATER AND THE OCCURRENCE OF SPONTANEOUS-ABORTION [J].
ASCHENGRAU, A ;
ZIERLER, S ;
COHEN, A .
ARCHIVES OF ENVIRONMENTAL HEALTH, 1989, 44 (05) :283-290
[5]   EPIDEMIOLOGIC STUDIES ON HUMAN-SUBJECTS EXPOSED TO ARSENIC IN DRINKING-WATER IN SOUTHEAST HUNGARY [J].
BORZSONYI, M ;
BERECZKY, A ;
RUDNAI, P ;
CSANADY, M ;
HORVATH, A .
ARCHIVES OF TOXICOLOGY, 1992, 66 (01) :77-78
[6]  
Casanueva E, 2003, J NUTR, V133, p1700S, DOI 10.1093/jn/133.5.1700S
[7]   Arsenic groundwater contamination in Middle Ganga Plain, Bihar, India: A future danger? [J].
Chakraborti, D ;
Mukherjee, SC ;
Pati, S ;
Sengupta, MK ;
Rahman, MM ;
Chowdhury, UK ;
Lodh, D ;
Chanda, CR ;
Chakraborty, AK ;
Basul, GK .
ENVIRONMENTAL HEALTH PERSPECTIVES, 2003, 111 (09) :1194-1201
[8]   Apoptosis and necrosis in developing brain cells due to arsenic toxicity and protection with antioxidants [J].
Chattopadhyay, S ;
Bhaumik, S ;
Purkayastha, M ;
Basu, S ;
Chaudhuri, AN ;
Das Gupta, S .
TOXICOLOGY LETTERS, 2002, 136 (01) :65-76
[9]   Determination of total arsenic concentrations in nails by inductively coupled plasma mass spectrometry [J].
Chen, KLB ;
Amarasiriwardena, CJ ;
Christiani, DC .
BIOLOGICAL TRACE ELEMENT RESEARCH, 1999, 67 (02) :109-125
[10]   Intra-individual variation in the metabolism of inorganic arsenic [J].
Concha, G ;
Vogler, G ;
Nermell, B ;
Vahter, M .
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH, 2002, 75 (08) :576-580
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