Association between height and osteoarthritis of the knee and hip: The Northern Finland Birth Cohort 1966 Study

被引:11
作者
Welling, Maiju [1 ,2 ,3 ,4 ]
Auvinen, Juha [1 ,2 ,5 ]
Lehenkari, Petri [6 ,7 ,8 ]
Mannikko, Minna [1 ,2 ,4 ]
Karppinen, Jaro [1 ,2 ,3 ,9 ]
Eskola, Pasi J. [1 ,2 ]
机构
[1] Oulu Univ Hosp, Ctr Life Course Hlth Res, Med Res Ctr Oulu, Oulu, Finland
[2] Univ Oulu, POB 5000, FI-90014 Oulu, Finland
[3] Oulu Univ Hosp, Med Res Ctr Oulu, Dept Phys & Rehabil Med, Oulu, Finland
[4] Univ Oulu, Fac Biochem & Mol Med, Oulu, Finland
[5] Oulu Univ Hosp, Unit Primary Care, Oulu, Finland
[6] Univ Oulu, Dept Anat & Cell Biol, Oulu, Finland
[7] Univ Oulu, Surg Clin, Med Res Ctr, Oulu, Finland
[8] Oulu Univ Hosp, Oulu, Finland
[9] Finnish Inst Occupat Hlth, Oulu, Finland
关键词
cohort studies; epidemiologic methods; hip; knee; osteoarthritis; BODY-MASS INDEX; MIDDLE-AGED WOMEN; RISK-FACTORS; RADIOGRAPHIC OSTEOARTHRITIS; EPIDEMIOLOGIC ASSESSMENT; POPULATION; INJURY; DISPARITIES; SMOKING; HISTORY;
D O I
10.1111/1756-185X.13059
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
ObjectivesTo investigate whether height at the age of 31 is associated with the incidence of knee and hip osteoarthritis (OA) in the following 15 years. MethodsParticipants in The Northern Finland Birth Cohort 1966 (NFBC1966) diagnosed with knee or hip OA between the ages of 31 and 46 were used as OA cases. Study subjects without knee and hip OA were used as the controls. Height and weight were measured in a clinical examination at the age of 31 (baseline). Mean heights for the OA cases and the controls were compared by an independent samples t-test. Cox regression analysis was performed to calculate the risk for OA for different height quartiles. The results were adjusted for body mass index/weight, education, smoking and leisure-time physical activity at baseline. Additionally, a Kaplan-Meier analysis was performed. ResultsMen with knee OA were 2.6 cm taller (P < 0.001) and women with knee OA 1.2 cm taller (P = 0.048) than the controls. Hip OA cases were found to be slightly shorter than the controls, but no statistically significant differences were observed. The adjusted hazard ratios (HRs) for knee OA and hip OA in the highest quartile were 2.5 (95% CI 1.4-4.5) and 1.0 (95% CI 0.3-3.4) for men and 1.8 (95% CI 1.0-3.1) and 0.7 (95% CI 0.2-2.3) for women. ConclusionsHeight at the age of 31 was associated with incidence of early knee OA, diagnosed prior to age 46. However, the low incidence of hip OA made our results for hip OA inconclusive.
引用
收藏
页码:1095 / 1104
页数:10
相关论文
共 35 条
[31]  
Wong L Y, 2015, East Asian Arch Psychiatry, V25, P150
[32]   Association of Knee Osteoarthritis with the Accumulation of Metabolic Risk Factors Such as Overweight, Hypertension, Dyslipidemia, and Impaired Glucose Tolerance in Japanese Men and Women: The ROAD Study [J].
Yoshimura, Noriko ;
Muraki, Shigeyuki ;
Oka, Hiroyuki ;
Kawaguchi, Hiroshi ;
Nakamura, Kozo ;
Akune, Toru .
JOURNAL OF RHEUMATOLOGY, 2011, 38 (05) :921-930
[33]   Role of Osteoarthritis, Comorbidity, and Pain in Determining Functional Limitations in Older Populations: European Project on Osteoarthritis [J].
Zambon, Sabina ;
Siviero, Paola ;
Denkinger, Michael ;
Limongi, Federica ;
Victoria Castell, Maria ;
van der Pas, Suzan ;
Otero, Angel ;
Edwards, Mark H. ;
Peter, Richard ;
Pedersen, Nancy L. ;
Sanchez-Martinez, Mercedes ;
Dennison, Elaine M. ;
Gesmundo, Antonella ;
Schaap, Laura A. ;
Deeg, Dorly J. H. ;
van Schoor, Natasja M. ;
Maggi, Stefania .
ARTHRITIS CARE & RESEARCH, 2016, 68 (06) :801-810
[34]   The Genetic Epidemiological Landscape of Hip and Knee Osteoarthritis: Where Are We Now and Where Are We Going? [J].
Zengini, Eleni ;
Finan, Chris ;
Wilkinson, J. Mark .
JOURNAL OF RHEUMATOLOGY, 2016, 43 (02) :260-266
[35]   Relationship between cigarette smoking and radiographic knee osteoarthritis in Chinese population: a cross-sectional study [J].
Zhang, Yi ;
Zeng, Chao ;
Li, Hui ;
Yang, Tuo ;
Deng, Zhen-han ;
Yang, Ye ;
Ding, Xiang ;
Xie, Dong-xing ;
Wang, Yi-lun ;
Lei, Guang-hua .
RHEUMATOLOGY INTERNATIONAL, 2015, 35 (07) :1211-1217