Novel derivatives of 3,5-di-tert-butylpyrocatechol with pharmacophore substituents

被引：4

作者：

Ukhin, L. Yu. ^{[1
]}

Kuz'mina, L. G. ^{[2
]}

Alexeenko, D. V. ^{[1
]}

Belousova, L. V. ^{[1
]}

Morkovnik, A. S. ^{[1
]}

Shepelenko, E. N. ^{[3
]}

Podshibyakin, V. A. ^{[1
]}

Borodkin, G. S. ^{[1
]}

Dmitrieva, O. I. ^{[1
]}

机构：

[1] Southern Fed Univ, Sci Res Inst Phys & Organ Chem, 194-2 Prosp Stachki, Rostov Na Donu 344090, Russia

[2] Russian Acad Sci, NS Kurnakov Inst Gen & Inorgan Chem, 31 Leninsky Prosp, Moscow 119991, Russia

[3] Russian Acad Sci, Fed Res Ctr Southern Sci Ctr, 41 Ul Chekhova, Rostov Na Donu 344006, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2019年 / 68卷 / 12期

关键词：

3; 5-di-tert-butyl-1; 2-benzoquinone; (4; 6-di-tert-butyl-2; 3-dihydroxyphenylthio)-acetic acid methyl ester; acid hydrazides; acetylcysteine derivatives; X-ray diffraction analysis; MEDICINAL CHEMISTRY;

D O I：

10.1007/s11172-019-2702-1

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New potentially bioactive derivatives comprising spatially hindered pyrocatechol linked to hydrazine, acid hydrazides (including isoniazid), and acetylcysteine by a covalent bridge, have been obtained. The structure of the obtained compounds was studied by X-ray diffraction analysis.

引用

页码：2290 / 2297

页数：8

共 15 条

[1]

[Anonymous], 1996, Russ. J. Gen. Chem

[2]

[Anonymous], LEKARSTVENNIE SREDST

[3]

[Anonymous], 1998, SMART SADABS SOFTW R

[4] OLEX2: a complete structure solution, refinement and analysis program [J].

Dolomanov, Oleg V. ;

Bourhis, Luc J. ;

Gildea, Richard J. ;

Howard, Judith A. K. ;

Puschmann, Horst .

JOURNAL OF APPLIED CRYSTALLOGRAPHY, 2009, 42 :339-341

[5] Silver(I) interaction and complexation with sterically hindered sulfur-containing diphenol derivatives [J].

Loginova, NV ;

Chernyavskaya , AA ;

Polozov, GI ;

Koval'chuk, TV ;

Bondarenko, EV ;

Osipovich, NP ;

Sheryakov, AA ;

Shadyro, OI .

POLYHEDRON, 2005, 24 (05) :611-618

[6]

Maslovskaya L.A., 1996, Russ. J. Gen. Chem, V66, P1847

[7]

Petrikevich D K, 1995, KHIM FARM ZH, V29, P841

[8]

SAINT, 2001, SAINT VERS 6 02A

[9]

SHELXTL-Plus, 1997, SHELXTL PLUS VERS 5

[10] Reactions of 3,5-di-tert-butyl-1,2-benzoquinone with mercapto carboxylic acids [J].

Ukhin, L. Yu. ;

Suponitsky, K. Yu. ;

Shepelenko, E. N. ;

Belousova, L. V. ;

Alekseenko, D. V. ;

Borodkin, G. S. ;

Etmetchenko, L. N. .

RUSSIAN CHEMICAL BULLETIN, 2016, 65 (03) :727-730

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