Novel derivatives of 3,5-di-tert-butylpyrocatechol with pharmacophore substituents

被引：4

作者：

Ukhin, L. Yu. ^{[1
]}

Kuz'mina, L. G. ^{[2
]}

Alexeenko, D. V. ^{[1
]}

Belousova, L. V. ^{[1
]}

Morkovnik, A. S. ^{[1
]}

Shepelenko, E. N. ^{[3
]}

Podshibyakin, V. A. ^{[1
]}

Borodkin, G. S. ^{[1
]}

Dmitrieva, O. I. ^{[1
]}

机构：

[1] Southern Fed Univ, Sci Res Inst Phys & Organ Chem, 194-2 Prosp Stachki, Rostov Na Donu 344090, Russia

[2] Russian Acad Sci, NS Kurnakov Inst Gen & Inorgan Chem, 31 Leninsky Prosp, Moscow 119991, Russia

[3] Russian Acad Sci, Fed Res Ctr Southern Sci Ctr, 41 Ul Chekhova, Rostov Na Donu 344006, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2019年 / 68卷 / 12期

关键词：

3; 5-di-tert-butyl-1; 2-benzoquinone; (4; 6-di-tert-butyl-2; 3-dihydroxyphenylthio)-acetic acid methyl ester; acid hydrazides; acetylcysteine derivatives; X-ray diffraction analysis; MEDICINAL CHEMISTRY;

D O I：

10.1007/s11172-019-2702-1

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New potentially bioactive derivatives comprising spatially hindered pyrocatechol linked to hydrazine, acid hydrazides (including isoniazid), and acetylcysteine by a covalent bridge, have been obtained. The structure of the obtained compounds was studied by X-ray diffraction analysis.

引用

页码：2290 / 2297

页数：8

共 6 条

[1] Novel derivatives of 3,5-di-tert-butylpyrocatechol with pharmacophore substituents
L. Yu. Ukhin
L. G. Kuz´mina
D. V. Alexeenko
L. V. Belousova
A. S. Morkovnik
E. N. Shepelenko
V. A. Podshibyakin
G. S. Borodkin
O. I. Dmitrieva
Russian Chemical Bulletin, 2019, 68 : 2290 - 2297
[2] Reactions of 4-acylresorcinol derivatives with 3,5-di-tert-butyl-4-hydroxybenzyl acetate
E. M. Kasymova
A. R. Burilov
L. I. Vagapova
N. A. Mukmeneva
S. V. Bukharov
G. N. Nugumanova
D. B. Krivolapov
M. A. Pudovik
I. A. Litvinov
A. I. Konovalov
Russian Chemical Bulletin, 2006, 55 : 1171 - 1176
[3] Synthesis and structure of new polynuclear cobalt(ii) complexes with 3,5-di-tert-butylbenzoic acid anions
E. N. Egorov
M. A. Kiskin
A. A. Sidorov
I. L. Eremenko
Russian Chemical Bulletin, 2013, 62 : 1924 - 1929
[4] The structure and intermolecular interactions of N,N′-bis-(3,5-di-tert-butyl-4-hydroxybenzyl)urea
G. N. Nugumanova
I. A. Litvinov
A. T. Gubaidullin
A. V. Chernova
R. R. Shagidullin
S. V. Bukharov
N. A. Mukmeneva
Journal of Structural Chemistry, 2006, 47 : 791 - 795
[5] The structure and intermolecular interactions of N,N′-bis-(3,5-di-tert-butyl-4-hydroxybenzyl)urea
Nugumanova, G. N.
Litvinov, I. A.
Gubaidullin, A. T.
Chernova, A. V.
Shagidullin, R. R.
Bukharov, S. V.
Mukmeneva, N. A.
JOURNAL OF STRUCTURAL CHEMISTRY, 2006, 47 (04) : 791 - 795
[6] Synthesis and biological evaluation of new 3,5-di(trifluoromethyl)-1,2,4-triazolesulfonylurea and thiourea derivatives as antidiabetic and antimicrobial agents
Faidallah, Hassan M.
Khan, Khalid A.
Asiri, Abdullah M.
JOURNAL OF FLUORINE CHEMISTRY, 2011, 132 (11) : 870 - 877

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