Probiotics for allergic diseases: Realities and myths

被引:31
作者
Yao, Tsung-Chieh [1 ,2 ,3 ]
Chang, Chee-Jen [4 ,5 ]
Hsu, Yi-Hsien [5 ]
Huang, Jing-Long [2 ,3 ]
机构
[1] Chang Gung Childrens Hosp, Div Allergy Asthma & Rheumatol, Dept Pediat, Tao Yuan, Taiwan
[2] Chang Gung Mem Hosp, Div Allergy Asthma & Rheumatol, Dept Pediat, Tao Yuan, Taiwan
[3] Chang Gung Univ Coll Med, Dept Pediat, Tao Yuan, Taiwan
[4] Chang Gung Univ, Grad Inst Clin Med Sci, Tao Yuan, Taiwan
[5] Chang Gung Mem Hosp, Bostat Ctr Clin Res, Tao Yuan, Taiwan
关键词
allergic disease; allergic rhinitis; allergy prevention; asthma; Lactobacillus; probiotics; LACTOBACILLUS-RHAMNOSUS GG; CHRONIC YOGURT CONSUMPTION; JAPANESE CEDAR POLLINOSIS; PLACEBO-CONTROLLED TRIAL; ACIDOPHILUS STRAIN L-92; RANDOMIZED DOUBLE-BLIND; ATOPIC-DERMATITIS; PRIMARY PREVENTION; INTESTINAL MICROFLORA; POLLEN ALLERGY;
D O I
10.1111/j.1399-3038.2009.00955.x
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
The prevalence of allergic diseases such as asthma, allergic rhinitis, and atopic dermatitis has increased sharply over the past two to three decades in many countries, and allergies are now the most common chronic disease among children throughout the world. In the past few years, probiotics have been advocated for the management of allergic diseases in many parts of the world. Physicians have a responsibility to ensure the efficacy and safety of any products they prescribe or recommend. This article provides a comprehensive overview and a critical interpretation of currently available evidence regarding the role of probiotics in the prevention and treatment of allergic diseases in humans and also discusses several major myths and potential risks associated with the use of probiotics. In the current era of evidence-based medicine, there is still insufficient evidence to recommend probiotics for the prevention of allergic diseases or as part of standard management for any allergic conditions in children.
引用
收藏
页码:900 / 919
页数:20
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