Influence of Sex on Treatment and Outcome in Chronic Heart Failure

被引：18
作者：
Frankenstein, Lutz [1 ]
Clark, Andrew L. [2 ]
Ribeiro, Jorge P. [3 ,4 ]
机构：
[1] Heidelberg Univ, Dept Cardiol, D-69120 Heidelberg, Germany
[2] Univ Hull, Dept Acad Cardiol, Kingston Upon Hull, Yorks, England
[3] Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Div Cardiol, Porto Alegre, RS, Brazil
[4] Univ Fed Rio Grande do Sul, Fac Med, Dept Med, Porto Alegre, RS, Brazil
来源：
CARDIOVASCULAR THERAPEUTICS | 2012年 / 30卷 / 03期
关键词：
Ace-inhibitor; Adherence; Aldosterone antagonist; Angiotensin receptor blocker; Beta-blocker; Gender; Heart failure; Medication; Outcome; Sex; Survival; Treatment; LEFT-VENTRICULAR DYSFUNCTION; CONVERTING-ENZYME-INHIBITORS; QUALITY-OF-CARE; SERUM DIGOXIN CONCENTRATION; GENDER-RELATED DIFFERENCES; RANDOMIZED-TRIAL; LONG-TERM; SYSTOLIC DYSFUNCTION; RECEPTOR BLOCKADE; EJECTION FRACTION;
D O I：
10.1111/j.1755-5922.2010.00253.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The population is aging, the prevalence of heart failure increases with age, and on average women live longer than men. There is evidence for sex-specific effects of individual, guideline-recommended drugs used for treatment of chronic heart failure. Women are underrepresented in most clinical trials and only a minority of drug applications to regulatory authorities have included sex analyses. The present review focuses on the potential female survival benefit in heart failure, the influence of sex on medical treatment in a broader sense, and the potential benefit to be derived from guideline recommended treatment and common adjunctive heart failure medication.
引用
收藏
页码：182 / 192
页数：11
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