Screening of pharmaceuticals and hormones at the regional scale, in surface and groundwaters intended to human consumption

被引：336
作者：
Vulliet, Emmanuelle [1 ]
Cren-Olive, Cecile [1 ]
机构：
[1] Inst Sci Anal, Dept Serv Cent Anal, UMR5280, F-69360 Solaize, France
来源：
ENVIRONMENTAL POLLUTION | 2011年 / 159卷 / 10期
关键词：
Pharmaceuticals; Hormones; Water supplies; SPE-LC-MS/MS; Risk assessment; SEWAGE-TREATMENT PLANTS; WASTE-WATER CONTAMINANTS; SOLID-PHASE EXTRACTION; PERSONAL CARE PRODUCTS; ENDOCRINE DISRUPTORS; NATIONAL RECONNAISSANCE; ENVIRONMENTAL WATERS; ESTROGENIC HORMONES; UNITED-STATES; DRUGS;
D O I：
10.1016/j.envpol.2011.04.033
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
As part of a regional screening to evaluate the risk, for the health of populations, to certain classes of emerging substances, several families of pharmaceuticals and hormones were looked for in waters intended to drinking. Thus, 52 substances were investigated in 71 surface waters and 70 groundwaters. Results indicate that no water was free of pollutants, regardless of its origin (surface or groundwater) and the season of collect. The pharmaceuticals most frequently detected and with the highest concentration levels were salicylic acid, carbamazepine and acetaminophen. Among hormones, testosterone, androstenedione and progesterone were detected in almost all the samples. Globally the groundwaters were less contaminated than surface waters in regards pharmaceuticals frequencies and levels. On the other side, androgens and progestagens were present with comparable frequencies and levels in both compartments. The risk linked to the presence of these substances on human health is discussed. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2929 / 2934
页数：6
相关论文
共 59 条
[1]   URINARY ESTROGEN PROFILE DETERMINATION IN YOUNG FINNISH VEGETARIAN AND OMNIVOROUS WOMEN [J].
ADLERCREUTZ, H ;
FOTSIS, T ;
BANNWART, C ;
HAMALAINEN, E ;
BLOIGU, S ;
OLLUS, A .
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1986, 24 (01) :289-296
[2]  
[Anonymous], 2006, RXLIST INTERNET DRUG
[3]   Monitoring of natural and synthetic hormones in a polluted river [J].
Barel-Cohen, K ;
Shore, LS ;
Shemesh, M ;
Wenzel, A ;
Mueller, J ;
Kronfeld-Schor, N .
JOURNAL OF ENVIRONMENTAL MANAGEMENT, 2006, 78 (01) :16-23
[4]   A national reconnaissance of pharmaceuticals and other organic wastewater contaminants in the United States - I) Groundwater [J].
Barnes, Kimberlee K. ;
Kolpin, Dana W. ;
Furlong, Edward T. ;
Zaugg, Steven D. ;
Meyer, Michael T. ;
Barber, Larry B. .
SCIENCE OF THE TOTAL ENVIRONMENT, 2008, 402 (2-3) :192-200
[5]   Monitoring natural and synthetic estrogens at activated sludge sewage treatment plants and in a receiving river water [J].
Baronti, C ;
Curini, R ;
D'Ascenzo, G ;
Di Corcia, A ;
Gentili, A ;
Samperi, R .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2000, 34 (24) :5059-5066
[6]  
Baselt RC., 2004, Disposition of Toxic Drugs and Chemicals in Man, V7th
[7]   Analysis and occurrence of estrogenic hormones and their glucuronides in surface water and waste water in The Netherlands [J].
Belfroid, AC ;
Van der Horst, A ;
Vethaak, AD ;
Schäfer, AJ ;
Rijs, GBJ ;
Wegener, J ;
Cofino, WP .
SCIENCE OF THE TOTAL ENVIRONMENT, 1999, 225 (1-2) :101-108
[8]   Analysis of multiple endocrine disruptors in environmental waters via wide-spectrum solid-phase extraction and dual-polarity ionization LC-ion trap-MS/MS [J].
Benijts, T ;
Lambert, W ;
De Leenheer, A .
ANALYTICAL CHEMISTRY, 2004, 76 (03) :704-711
[9]   Human pharmaceuticals in surface waters implementation of a prioritization methodology and application to the French situation [J].
Besse, Jean-Philippe ;
Garric, Jeanne .
TOXICOLOGY LETTERS, 2008, 176 (02) :104-123
[10]   Waste-Indicator and Pharmaceutical Compounds in Landfill-Leachate-Affected Ground Water near Elkhart, Indiana, 2000-2002 [J].
Buszka, P. M. ;
Yeskis, D. J. ;
Kolpin, D. W. ;
Furlong, E. T. ;
Zaugg, S. D. ;
Meyer, M. T. .
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 2009, 82 (06) :653-659
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