Emerging Roles of Ganoderma Lucidum in Anti-Aging

被引：120
作者：
Wang, Jue [1 ,2 ]
Cao, Bin [1 ]
Zhao, Haiping [2 ]
Feng, Juan [1 ]
机构：
[1] China Med Univ, Shengjing Hosp, Dept Neurol, Shenyang 110004, Liaoning, Peoples R China
[2] Capital Med Univ, Cerebrovasc Dis Res Inst, Xuanwu Hosp, Beijing 100053, Peoples R China
来源：
AGING AND DISEASE | 2017年 / 8卷 / 06期
关键词：
Ganoderma lucidum; anti-aging; antioxidant; immunomodulation; anti-neurodegeneration; REISHI MEDICINAL MUSHROOM; ALPHA-LIPOIC ACID; AGING RAT-HEART; NF-KAPPA-B; OXIDATIVE STRESS; ATRUM POLYSACCHARIDE; ANTIOXIDANT ACTIVITY; STRUCTURAL-CHARACTERIZATION; MITOCHONDRIAL DYSFUNCTION; DIETARY SUPPLEMENTATION;
D O I：
10.14336/AD.2017.0410
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Ganoderma lucidum is a white-rot fungus that has been viewed as a traditional Chinese tonic for promoting health and longevity. It has been revealed that several extractions from Ganoderma lucidum, such as Ethanol extract, aqueous extract, mycelia extract, water soluble extract of the culture medium of Ganoderma lucidum mycelia, Ganodermasides A, B, C, D, and some bioactive components of Ganoderma lucidum, including Reishi Polysaccharide Fraction 3, Ganoderma lucidum polysaccharides I, II, III, IV, Ganoderma lucidum peptide, Ganoderma polysaccharide peptide, total G. lucidum triterpenes and Ganoderic acid C1 could exert lifespan elongation or related activities. Although the use of Ganoderma lucidum as an elixir has been around for thousands of years, studies revealing its effect of lifespan extension are only the tip of the iceberg. Besides which, the kinds of extractions or components being comfrimed to be anti-aging are too few compared with the large amounts of Ganoderma lucidum extractions or constituients being discovered. This review aims to lay the ground for fully elucidating the potential mechanisms of Ganoderma lucidum underlying anti-aging effect and its clinical application.
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页码：691 / 707
页数：17
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