WormBase: a modern Model Organism Information Resource

被引：203

作者：

Harris, Todd W. ^{[1
]}

Arnaboldi, Valerio ^{[2
]}

Cain, Scott ^{[1
]}

Chan, Juancarlos ^{[2
]}

Chen, Wen J. ^{[2
]}

Cho, Jaehyoung ^{[2
]}

Davis, Paul ^{[3
]}

Gao, Sibyl ^{[1
]}

Grove, Christian A. ^{[2
]}

Kishore, Ranjana ^{[2
]}

Lee, Raymond Y. N. ^{[2
]}

Muller, Hans-Michael ^{[2
]}

Nakamura, Cecilia ^{[2
]}

Nuin, Paulo ^{[1
]}

Paulini, Michael ^{[3
]}

Raciti, Daniela ^{[2
]}

Rodgers, Faye H. ^{[4
]}

Russell, Matthew ^{[3
]}

Schindelman, Gary ^{[2
]}

Auken, Kimberly, V ^{[2
]}

Wang, Qinghua ^{[2
]}

Williams, Gary ^{[3
]}

Wright, Adam J. ^{[1
]}

Yook, Karen ^{[2
]}

Howe, Kevin L. ^{[3
]}

Schedl, Tim ^{[5
]}

Stein, Lincoln ^{[1
]}

Sternberg, Paul W. ^{[2
]}

机构：

[1] Ontario Inst Canc Res, Informat & Biocomp Platform, Toronto, ON M5G 0A3, Canada

[2] CALTECH, Div Biol & Biol Engn 156 29, Pasadena, CA 91125 USA

[3] European Bioinformat Inst, European Mol Biol Lab, Wellcome Trust Genome Campus, Cambridge CB10 1SD, England

[4] Wellcome Trust Sanger Inst, Wellcome Trust Genome Campus, Cambridge CB10 1SA, England

[5] Washington Univ, Sch Med, Dept Genet, St Louis, MO 63110 USA

来源：

NUCLEIC ACIDS RESEARCH | 2020年 / 48卷 / D1期

基金：

英国生物技术与生命科学研究理事会; 英国医学研究理事会;

关键词：

GENOME; ONTOLOGY; DATABASE;

D O I：

10.1093/nar/gkz920

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

WormBase (https://wormbase.org/) is a mature Model Organism Information Resource supporting researchers using the nematode Caenorhabditis elegans as a model system for studies across a broad range of basic biological processes. Toward this mission, WormBase efforts are arranged in three primary facets: curation, user interface and architecture. In this update, we describe progress in each of these three areas. In particular, we discuss the status of literature curation and recently added data, detail new features of the web interface and options for users wishing to conduct data mining workflows, and discuss our efforts to build a robust and scalable architecture by leveraging commercial cloud offerings. We conclude with a description of WormBase's role as a founding member of the nascent Alliance of Genome Resources.

引用

页码：D762 / D767

页数：6

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