Understanding the Association Between Negative Symptoms and Performance on Effort-Based Decision-Making Tasks: The Importance of Defeatist Performance Beliefs

被引:37
作者
Reddy, L. Felice [1 ,2 ]
Horan, William P. [1 ,2 ]
Barch, Deanna M. [3 ,4 ,5 ]
Buchanan, Robert W. [6 ]
Gold, James M. [6 ]
Marder, Stephen R. [1 ,2 ]
Wynn, Jonathan K. [1 ,2 ]
Young, Jared [7 ,8 ]
Green, Michael F. [1 ,2 ]
机构
[1] Dept Vet Affairs, VISN Mental Illness Res Educ & Clin Ctr 22, Los Angeles, CA 91343 USA
[2] Univ Calif Los Angeles, David Geffen Sch Med, Semel Inst Neurosci & Human Behav, Los Angeles, CA 90095 USA
[3] Washington Univ, Dept Psychol, St Louis, MO 63130 USA
[4] Washington Univ, Dept Psychiat, St Louis, MO USA
[5] Washington Univ, Dept Radiol, St Louis, MO USA
[6] Univ Maryland, Sch Med, Dept Psychiat, Maryland Psychiat Res Ctr, Baltimore, MD 21201 USA
[7] Univ Calif San Diego, Dept Psychiat, San Diego, CA 92103 USA
[8] VA San Diego Healthcare Syst, Res Serv, San Diego, CA USA
关键词
motivation; avolition; deck choice effort task; EFFORT ALLOCATION; CLINICAL-TRIALS; SCHIZOPHRENIA; COST; MOTIVATION; COMPUTATION; AMOTIVATION; PREDICTORS; PARADIGMS; ATTITUDES;
D O I
10.1093/schbul/sbx156
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Effort-based decision-making paradigms are increasingly utilized to gain insight into the nature of motivation deficits. Research has shown associations between effort-based decision making and experiential negative symptoms; however, the associations are not consistent. The current study had two primary goals. First, we aimed to replicate previous findings of a deficit in effort-based decision making among individuals with schizophrenia on a test of cognitive effort. Second, in a large sample combined from the current and a previous study, we sought to examine the association between negative symptoms and effort by including the related construct of defeatist beliefs. The results replicated previous findings of impaired cognitive effort-based decision making in schizophrenia. Defeatist beliefs significantly moderated the association between negative symptoms and effort-based decision making such that there was a strong association between high negative symptoms and deficits in effort-based decision making, but only among participants with high levels of defeatist beliefs. Thus, our findings suggest the relationship between negative symptoms and effort performance may be understood by taking into account the role of defeatist beliefs, and finding that might explain discrepancies in previous studies.
引用
收藏
页码:1217 / 1226
页数:10
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