Weight of evidence needed to substantiate a health effect for probiotics and prebiotics - Regulatory considerations in Canada, EU, and US

被引：25
作者：
Sanders, ME
Tompkins, T
Heimbach, JT
Kolida, S
机构：
[1] Dairy & Food Culture Technol, Centennial, CO 80122 USA
[2] Inst Rosell, Montreal, PQ, Canada
[3] JHeimbach LLC, Washington, DC USA
[4] Univ Reading, Sch Food Biosci, Food Microbial Sci Unit, Reading, Berks, England
来源：
EUROPEAN JOURNAL OF NUTRITION | 2005年 / 44卷 / 05期
关键词：
probiotics; prebiotics; regulatory; health claims;
D O I：
10.1007/s00394-004-0527-6
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
Successful and responsible introduction of probiotic and prebiotic products into the worldwide marketplace requires labelling for health benefits that meets consumer needs, adheres to regulatory standards and does not overextend scientific evidence. Regulations differ among countries, but underlying all is an emphasis on scientific credibility of any statements of health benefits. This paper considers the value of different types of evidence offered in substantiation of efficacy and reviews different regulatory approaches to labelling for health claims. Limitations of in vitro, animal and different types of human studies used for efficacy substantiation for probiotics and prebiotics are discussed.
引用
收藏
页码：303 / 310
页数：8
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