An international consensus statement on the management of postoperative anaemia after major surgical procedures

被引:195
作者
Munoz, M. [1 ]
Acheson, A. G. [2 ]
Bisbe, E. [3 ]
Butcher, A. [4 ]
Gomez-Ramirez, S. [5 ]
Khalafallah, A. A. [6 ,7 ]
Kehlet, H. [8 ]
Kietaibl, S. [9 ]
Liumbruno, G. M. [10 ]
Meybohm, P. [11 ]
Baikady, R. Rao [12 ]
Shander, A. [13 ,14 ]
So-Osman, C. [15 ,16 ]
Spahn, D. R. [17 ,18 ]
Klein, A. A. [19 ]
机构
[1] Univ Malaga, Sch Med, Dept Surg Specialties Biochem & Immunol, Malaga, Spain
[2] Nottingham Univ Hosp, Natl Inst Hlth Res Biomed Res Unit, Nottingham Digest Dis Ctr, Dept Colorectal Surg, Nottingham, England
[3] Univ Hosp Mar Esperanza, Dept Anaesthesia, Barcelona, Spain
[4] UCL, Div Surg, London, England
[5] Univ Hosp Virgen de la Victoria, Dept Internal Med, Malaga, Spain
[6] Launceston Gen Hosp, Dept Haematol & Med, Launceston, Tas, Australia
[7] Univ Tasmania, Menzies Inst Med Res, Hobart, Tas, Australia
[8] Copenhagen Univ Hosp, Rigshosp, Sect Surg Pathophysiol, Copenhagen, Denmark
[9] Evangel Hosp, Dept Anaesthesia & Intens Care, Vienna, Austria
[10] Natl Inst Hlth, Italian Natl Blood Ctr, Rome, Italy
[11] Univ Hosp Frankfurt, Dept Anaesthesiol Intens Care Med & Pain Therapy, Frankfurt, Germany
[12] Royal Marsden NHS Fdn Trust, Dept Anaesthesia, London, England
[13] Englewood Hosp & Med Ctr, Anaesthesiol Crit Care & Hyperbar Med, Englewood, NJ USA
[14] TeamHlth Res Inst, Englewood, NJ USA
[15] Sanquin Blood Bank, Dept Transfus Med, Amsterdam, Netherlands
[16] Groene Hart Hosp, Dept Internal Med, Gouda, Netherlands
[17] Univ Hosp Zurich, Inst Anaesthesiol, Zurich, Switzerland
[18] Univ Hosp Zurich, Anaesthesiol Intens Care Med & Operating Room Man, Zurich, Switzerland
[19] Royal Papworth Hosp, Dept Anaesthesia & Intens Care, Cambridge, England
基金
瑞士国家科学基金会;
关键词
anaemia; erythropoiesis stimulating agents; iron deficiency; iron supplementation; postoperative period; transfusion; PATIENT BLOOD MANAGEMENT; INTRAVENOUS IRON THERAPY; FAST-TRACK HIP; FERRIC CARBOXYMALTOSE; CARDIAC-SURGERY; TRANSFUSION REQUIREMENTS; ORAL IRON; CELL TRANSFUSION; PERIOPERATIVE ERYTHROPOIETIN; ORTHOPEDIC-SURGERY;
D O I
10.1111/anae.14358
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Despite numerous guidelines on the management of anaemia in surgical patients, there is no pragmatic guidance for the diagnosis and management of anaemia and iron deficiency in the postoperative period. A number of experienced researchers and clinicians took part in a two-day expert workshop and developed the following consensus statement. After presentation of our own research data and local policies and procedures, appropriate relevant literature was reviewed and discussed. We developed a series of best-practice and evidence-based statements to advise on patient care with respect to anaemia and iron deficiency in the postoperative period. These statements include: a diagnostic approach to iron deficiency and anaemia in surgical patients; identification of patients appropriate for treatment; and advice on practical management and follow-up that is easy to implement. Available data allow the fulfilment of the requirements of Pillar 1 of Patient Blood Management. We urge national and international research funding bodies to take note of these recommendations, particularly in terms of funding large-scale prospective, randomised clinical trials that can most effectively address the important clinical questions and this clearly unmet medical need.
引用
收藏
页码:1418 / 1431
页数:14
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