Effect of glycyrrhizic acid on lappaconitine phototransformation

被引：34

作者：

Kornievskaya, Valeria S. ^{[1
]}

Kruppa, Alexander I. ^{[1
]}

Polyakov, Nicholas E. ^{[1
]}

Leshina, Tatyana V. ^{[1
]}

机构：

[1] Inst Chem Kinet & Combust, Novosibirsk 630090, Russia

来源：

JOURNAL OF PHYSICAL CHEMISTRY B | 2007年 / 111卷 / 39期

关键词：

D O I：

10.1021/jp0739770

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

H-1 NMR and CIDNP methods were used to demonstrate that triterpene glycoside (glycyrrhizic acid, GA) can substantially change the efficiency and direction of phototransformation of alkaloid lappaconitine (LA) due to both its solubilization in GA micelles and protonation of LA amine nitrogen in water-alcohol solutions. The LA solubilization in the GA micelle suppresses the process of deacylation.

引用

页码：11447 / 11452

页数：6

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