Electronic interfaces switchable by logically processed multiple biochemical and physiological signals

被引:41
作者
Katz, Evgeny [1 ,2 ]
Bocharova, Vera [1 ,2 ]
Privman, Marina [3 ]
机构
[1] Clarkson Univ, Dept Chem & Biomol Sci, Potsdam, NY 13699 USA
[2] Clarkson Univ, NanoBio Lab, Potsdam, NY 13699 USA
[3] SUNY Empire State Coll, Ft Drum, NY 13602 USA
基金
美国国家科学基金会;
关键词
REGULATED BIOELECTRONIC DEVICES; BIOFUEL CELL; NOISE-REDUCTION; AMPEROMETRIC TRANSDUCTION; ADAPTIVE NANOWIRES; MOLECULAR LOGIC; POLYMER; SYSTEM; GATES; AMPLIFICATION;
D O I
10.1039/c2jm30172e
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Interdisciplinary research integrating biochemistry, electrochemistry, materials science and unconventional computer science has resulted in the development of electrodes and semiconductor devices functionalized with stimuli-responsive materials. Their coupling to biomolecular information processing systems allows biological control of electronics. Biochemical signals logically processed by cascades of enzyme-biocatalyzed reactions have enabled pre-programmed switching of bioelectronic interfaces. Concentration changes of biomarkers signaling medical dysfunctions have been transduced to amplified electronic signals at switchable bioelectronic interfaces. Multi-signal biosensors and switchable biofuel cells controlled by biochemical signals have thus been realized.
引用
收藏
页码:8171 / 8178
页数:8
相关论文
共 67 条
[41]   Switchable Electrode Controlled by Enzyme Logic Network System: Approaching Physiologically Regulated Bioelectronics [J].
Privman, Marina ;
Tam, Tsz Kin ;
Pita, Marcos ;
Katz, Evgeny .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (03) :1314-1321
[42]   Optimization of enzymatic biochemical logic for noise reduction and scalability: How many biocomputing gates can be interconnected in a circuit? [J].
Privman, Vladimir ;
Strack, Guinevere ;
Solenov, Dmitry ;
Pita, Marcos ;
Katz, Evgeny .
JOURNAL OF PHYSICAL CHEMISTRY B, 2008, 112 (37) :11777-11784
[43]   Control of Noise in Chemical and Biochemical Information Processing [J].
Privman, Vladimir .
ISRAEL JOURNAL OF CHEMISTRY, 2011, 51 (01) :118-131
[44]   Realization and Properties of Biochemical-Computing Biocatalytic XOR Gate Based on Signal Change [J].
Privman, Vladimir ;
Zhou, Jian ;
Halamek, Jan ;
Katz, Evgeny .
JOURNAL OF PHYSICAL CHEMISTRY B, 2010, 114 (42) :13601-13608
[45]   Network Analysis of Biochemical Logic for Noise Reduction and Stability: A System of Three Coupled Enzymatic AND Gates [J].
Privman, Vladimir ;
Arugula, Mary A. ;
Halamek, Jan ;
Pita, Marcos ;
Katz, Evgeny .
JOURNAL OF PHYSICAL CHEMISTRY B, 2009, 113 (15) :5301-5310
[46]   Determination of formal potential of NADH/NAD+ redox couple and catalytic oxidation of NADH using poly(phenosafranin)-modified carbon electrodes [J].
Saleh, Farhana S. ;
Rahman, Mohammad R. ;
Okajima, Takeyoshi ;
Mao, Lanqun ;
Ohsaka, Takeo .
BIOELECTROCHEMISTRY, 2011, 80 (02) :121-127
[47]   A deoxyribozyme-based molecular automaton [J].
Stojanovic, MN ;
Stefanovic, D .
NATURE BIOTECHNOLOGY, 2003, 21 (09) :1069-1074
[48]   Artificial Muscle Reversibly Controlled by Enzyme Reactions [J].
Strack, Guinevere ;
Bocharova, Vera ;
Arugula, Mary A. ;
Pita, Marcos ;
Halamek, Jan ;
Katz, Evgeny .
JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2010, 1 (05) :839-843
[49]   Logic Networks Based on Immunorecognition Processes [J].
Strack, Guinevere ;
Chinnapareddy, Soujanya ;
Volkov, Dmytro ;
Halamek, Jan ;
Pita, Marcos ;
Sokolov, Igor ;
Katz, Evgeny .
JOURNAL OF PHYSICAL CHEMISTRY B, 2009, 113 (35) :12154-12159
[50]  
Stuart MAC, 2010, NAT MATER, V9, P101, DOI [10.1038/NMAT2614, 10.1038/nmat2614]