Electronic interfaces switchable by logically processed multiple biochemical and physiological signals

被引:41
作者
Katz, Evgeny [1 ,2 ]
Bocharova, Vera [1 ,2 ]
Privman, Marina [3 ]
机构
[1] Clarkson Univ, Dept Chem & Biomol Sci, Potsdam, NY 13699 USA
[2] Clarkson Univ, NanoBio Lab, Potsdam, NY 13699 USA
[3] SUNY Empire State Coll, Ft Drum, NY 13602 USA
基金
美国国家科学基金会;
关键词
REGULATED BIOELECTRONIC DEVICES; BIOFUEL CELL; NOISE-REDUCTION; AMPEROMETRIC TRANSDUCTION; ADAPTIVE NANOWIRES; MOLECULAR LOGIC; POLYMER; SYSTEM; GATES; AMPLIFICATION;
D O I
10.1039/c2jm30172e
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Interdisciplinary research integrating biochemistry, electrochemistry, materials science and unconventional computer science has resulted in the development of electrodes and semiconductor devices functionalized with stimuli-responsive materials. Their coupling to biomolecular information processing systems allows biological control of electronics. Biochemical signals logically processed by cascades of enzyme-biocatalyzed reactions have enabled pre-programmed switching of bioelectronic interfaces. Concentration changes of biomarkers signaling medical dysfunctions have been transduced to amplified electronic signals at switchable bioelectronic interfaces. Multi-signal biosensors and switchable biofuel cells controlled by biochemical signals have thus been realized.
引用
收藏
页码:8171 / 8178
页数:8
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