DISORDERS IN PROGRAMMED CELL DEATH REGULATION IN ACUTE LEUKEMIA

被引：0
作者：
Khodunova, E. E. [1 ]
Parovichnikova, E. N. [1 ]
机构：
[1] Hematol Res Ctr, Moscow, Russia
来源：
GEMATOLOGIYA I TRANSFUZIOLOGIYA | 2011年 / 56卷 / 04期
关键词：
acute leukemia; carcinogenesis; apoptosis; apoptosis regulation disorders; angiotensin-converting enzyme; ANGIOTENSIN-CONVERTING ENZYME; ACUTE MYELOID-LEUKEMIA; HEMATOPOIETIC STEM-CELLS; FAS ANTIGEN; DIFFERENTIAL EXPRESSION; INDUCED APOPTOSIS; PERIPHERAL-BLOOD; P53; MUTATIONS; BCL-2; FAMILY; PROTEIN;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Basic approaches to regulation of programmed cell death (apoptosis) are discussed. Apoptosis plays the key role in the regulation of hemopoietic cell proliferation, differentiation, and viability. The mechanisms of apoptosis regulation are disordered in acute leukemia, which causes the development of the leukemic clone and determines its resistance to cytostatic therapy.
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页码：22 / 30
页数：9
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