Prevalence of carriage of extended-spectrum β-lactamase-producing enterobacteria and associated factors in a French hospital

被引：14
作者：
Jolivet, S. [1 ,2 ]
Vaillant, L. [2 ]
Poncin, T. [3 ]
Lolom, I. [2 ]
Gaudonnet, Y. [2 ]
Rondinaud, E. [1 ,3 ]
Bendjelloul, G. [2 ]
Lomont, A. [2 ]
Lucet, J. -C. [1 ,2 ]
Armand-Lefevre, L. [1 ,3 ]
机构：
[1] Univ Paris Diderot, Sorbonne Paris Cite, INSERM, IAME,UMR 1137, Paris, France
[2] Hop Bichat Claude Bernard, AP HP, Infect Control Unit, Paris, France
[3] Hop Bichat Claude Bernard, AP HP, Bacteriol Lab, Paris, France
来源：
CLINICAL MICROBIOLOGY AND INFECTION | 2018年 / 24卷 / 12期
关键词：
Associated factors; Carriage; Enterobacteriaceae; Extended-spectrum beta-lactamase (ESBL)-producing enterobacteria; Prevalence; ESCHERICHIA-COLI; RESISTANT ENTEROBACTERIACEAE; TRANSMISSION; INFECTIONS; COMMUNITY;
D O I：
10.1016/j.cmi.2018.03.008
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Objectives: Our aim was to evaluate the prevalence and associated factors for carriage of extended-spectrum beta-lactamase-producing enterobacteria (ESBL-PE) in a healthcare facility. Methods: In 2016 a serial cross-sectional survey of ESBL-PE carriage in a French university hospital was conducted. All patients present on the day of the survey were screened for ESBL-PE carriage. Demographic characteristics and risk factors for ESBL-PE carriage were collected. Results: In all, 146/844 patients (17%) were digestive carriers of ESBL-PE; of these, 96 (66%) had not previously been identified. Among patients carrying ESBL-PE, Escherichia coli (62%) and CTX-M type (94%) predominated. Greater age, recent travel abroad, receipt of antibiotic, and prolonged hospitalization were associated with ESBL-PE carriage. Conclusion: Given the high prevalence of ESBL-PE and the high proportion of unknown carriers, our results strongly suggest reinforcing standard precautions rather than contact precautions for controlling the spread of ESBL-PE. (C) 2018 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：1311 / 1314
页数：4
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