FTY720 inhibits the mRNA expression of intragraft cytotoxic molecules, leading to cardiac allograft survival

被引：3
作者：
Nakajima, H [1 ]
Sun, E [1 ]
Mizuta, N [1 ]
Fujiwara, I [1 ]
Oka, T [1 ]
机构：
[1] Kyoto Prefectural Univ Med, Dept Surg 2, Kamikyo Ku, Kyoto 602, Japan
来源：
TRANSPLANTATION PROCEEDINGS | 1998年 / 30卷 / 05期
关键词：
D O I：
10.1016/S0041-1345(98)00595-8
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页码：2217 / 2220
页数：4
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共 15 条
  • [1] The relationship of granzyme A and perforin expression to cardiac allograft rejection and dysfunction
    Alpert, S
    Lewis, NP
    Ross, H
    Fowler, M
    Valantine, HA
    [J]. TRANSPLANTATION, 1995, 60 (12) : 1478 - 1485
  • [2] CD4-POSITIVE HELPER T-LYMPHOCYTES MEDIATE MOUSE CARDIAC ALLOGRAFT-REJECTION INDEPENDENT OF DONOR ALLOANTIGEN-SPECIFIC CYTOTOXIC T-LYMPHOCYTES
    BISHOP, DK
    CHAN, S
    LI, WH
    ENSLEY, RD
    XU, SX
    EICHWALD, EJ
    [J]. TRANSPLANTATION, 1993, 56 (04) : 892 - 897
  • [3] Induction of selective cell death targeting on mature T-lymphocytes in rats by a novel immunosuppressant, FTY720
    Enosawa, S
    Suzuki, S
    Kakefuda, T
    Li, XK
    Amemiya, H
    [J]. IMMUNOPHARMACOLOGY, 1996, 34 (2-3): : 171 - 179
  • [4] GRANZYME-A AND PERFORIN AS MARKERS FOR REJECTION IN CARDIAC TRANSPLANTATION
    GRIFFITHS, GM
    NAMIKAWA, R
    MUELLER, C
    LIU, CC
    YOUNG, JDE
    BILLINGHAM, M
    WEISSMAN, I
    [J]. EUROPEAN JOURNAL OF IMMUNOLOGY, 1991, 21 (03) : 687 - 692
  • [5] MECHANISM OF LYMPHOCYTE-MEDIATED CYTO-TOXICITY
    HENKART, PA
    [J]. ANNUAL REVIEW OF IMMUNOLOGY, 1985, 3 : 31 - 58
  • [6] FAS-MEDIATED CYTOTOXICITY - AN IMMUNOEFFECTOR OR IMMUNOREGULATORY PATHWAY IN T-CELL-MEDIATED IMMUNE-RESPONSES
    LARSEN, CP
    ALEXANDER, DZ
    HENDRIX, R
    RITCHIE, SC
    PEARSON, TC
    [J]. TRANSPLANTATION, 1995, 60 (03) : 221 - 224
  • [7] GRANZYME-B AND PERFORIN CAN BE USED AS PREDICTIVE MARKERS OF ACUTE REJECTION IN HEART-TRANSPLANTATION
    LEGROSMAIDA, S
    SOULIE, A
    BENVENUTI, C
    WARGNIER, A
    VALLEE, N
    BERTHOU, C
    GUILLET, J
    SASPORTES, M
    SIGAUX, N
    [J]. EUROPEAN JOURNAL OF IMMUNOLOGY, 1994, 24 (01) : 229 - 233
  • [8] CYTOLYTIC T-CELL CYTOTOXICITY IS MEDIATED THROUGH PERFORIN AND FAS LYTIC PATHWAYS
    LOWIN, B
    HAHNE, M
    MATTMANN, C
    TSCHOPP, J
    [J]. NATURE, 1994, 370 (6491) : 650 - 652
  • [9] SYNERGISTIC ROLES OF GRANZYME-A AND GRANZYME-B IN MEDIATING TARGET-CELL DEATH BY RAT BASOPHILIC LEUKEMIA MAST-CELL TUMORS ALSO EXPRESSING CYTOLYSIN PERFORIN
    NAKAJIMA, H
    PARK, HL
    HENKART, PA
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1995, 181 (03) : 1037 - 1046
  • [10] SELVAGGI G, 1996, TRANSPLANTATION, V62, P1915
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