Temporal order memory differences in Alzheimer's disease and vascular dementia

被引：18

作者：

Hampstead, Benjamin M. ^{[1
,2
]}

Libon, David J. ^{[3
]}

Moelter, Stephen T. ^{[4
]}

Swirsky-Sacchetti, Thomas ^{[5
]}

Scheffer, Ludo ^{[6
]}

Platek, Steven M. ^{[7
]}

Chute, Douglas ^{[6
]}

机构：

[1] Atlanta VA Med Ctr, VA RR&D Ctr Excellence, Decatur, GA USA

[2] Emory Univ, Sch Med, Dept Rehabil Med, Atlanta, GA USA

[3] Drexel Univ, Coll Med, Dept Neurol, Philadelphia, PA 19104 USA

[4] Univ Sci Philadelphia, Hlth Psychol Program, Philadelphia, PA USA

[5] Thomas Jefferson Univ, Jefferson Med Coll, Dept Psychiat & Human Behav, Philadelphia, PA 19107 USA

[6] Drexel Univ, Philadelphia, PA 19104 USA

[7] Georgia Gwinnett Coll, Lawrenceville, GA USA

来源：

JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY | 2010年 / 32卷 / 06期

关键词：

Small vessel ischemic disease; Sequential memory; Working memory; Mild cognitive impairment; Leukoaraiosis; MILD COGNITIVE IMPAIRMENT; MEDIAL PREFRONTAL CORTEX; VERBAL WORKING-MEMORY; RECOGNITION MEMORY; BINSWANGERS-DISEASE; PARKINSONS-DISEASE; BRAIN; LEUKOARAIOSIS; VALIDATION; MECHANISMS;

D O I：

10.1080/13803390903418918

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

Determining the order of events is essential for accurate memory recollection: an ability previously linked to both frontal and medial temporal functioning. Frontal-subcortical and medial temporal dysfunction typify vascular dementia (VaD) and Alzheimer's disease (AD), respectively. Therefore, we assessed patients' ordering abilities using a novel sequencing task that progressively increased memory load. VaD patients made more errors and selected more previously encountered stimuli than did AD. Curve analysis revealed a general decline in ordering for VaD whereas error production in AD is more dependent on memory load. These findings generally support the role of frontal-subcortical functioning in temporal order memory.

引用

页码：645 / 654

页数：10

共 66 条

[31] Inhibition in verbal working memory revealed by brain activation [J].

Jonides, J ;

Smith, EE ;

Marshuetz, C ;

Koeppe, RA ;

Reuter-Lorenz, PA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (14) :8410-8413

[32] LEUKO-ARAIOSIS ON MAGNETIC-RESONANCE-IMAGING AND SPEED OF MENTAL PROCESSING [J].

JUNQUE, C ;

PUJOL, J ;

VENDRELL, P ;

BRUNA, O ;

JODAR, M ;

RIBAS, JC ;

VINAS, J ;

CAPDEVILA, A ;

MARTIVILALTA, JL .

ARCHIVES OF NEUROLOGY, 1990, 47 (02) :151-156

[33] Characterizing alterations in executive functioning across distinct subtypes of cortical and subcortical dementia [J].

Lamar, M ;

Swenson, R ;

Kaplan, E ;

Libon, DJ .

CLINICAL NEUROPSYCHOLOGIST, 2004, 18 (01) :22-31

[34] Capacity to maintain mental set in dementia [J].

Lamar, M ;

Price, CC ;

Davis, KL ;

Kaplan, E ;

Libon, DJ .

NEUROPSYCHOLOGIA, 2002, 40 (04) :435-445

[35] Alterations in working memory as a function of leukoaraiosis in dementia [J].

Lamar, Melissa ;

Price, Catherine C. ;

Libon, David J. ;

Penney, Dana L. ;

Kaplan, Edith ;

Grossman, Murray ;

Heilman, Kenneth M. .

NEUROPSYCHOLOGIA, 2007, 45 (02) :245-254

[36] Linking MRI hyperintensities with patterns of neuropsychological impairment - Evidence for a threshold effect [J].

Libon, David J. ;

Price, Catherine C. ;

Giovannetti, Tania ;

Swenson, Rodney ;

Bettcher, Brianne Magouirk ;

Heilman, Kenneth M. ;

Pennisi, Alfio .

STROKE, 2008, 39 (03) :806-813

[37] From Binswanger's disease to leuokoaraiosis: What we have learned about subcortical vascular dementia [J].

Libon, DJ ;

Price, CC ;

Garrett, KD ;

Giovannetti, T .

CLINICAL NEUROPSYCHOLOGIST, 2004, 18 (01) :83-100

[38]

LIBON DJ, 1996, ARCH CLIN NEUROPSYCH, V11, P193

[39] Differentiation of vascular dementia from AD on neuropsychological tests [J].

Looi, JCL ;

Sachdev, PS .

NEUROLOGY, 1999, 53 (04) :670-678

[40] THE TEMPORAL-DISTANCE EFFECT IN SUBJECTS WITH DEMENTIA OF THE ALZHEIMER-TYPE [J].

MADSEN, J ;

KESNER, RP .

ALZHEIMER DISEASE & ASSOCIATED DISORDERS, 1995, 9 (02) :94-100

← 1 2 3 4 5 6 7 →