Temporal order memory differences in Alzheimer's disease and vascular dementia

被引：18

作者：

Hampstead, Benjamin M. ^{[1
,2
]}

Libon, David J. ^{[3
]}

Moelter, Stephen T. ^{[4
]}

Swirsky-Sacchetti, Thomas ^{[5
]}

Scheffer, Ludo ^{[6
]}

Platek, Steven M. ^{[7
]}

Chute, Douglas ^{[6
]}

机构：

[1] Atlanta VA Med Ctr, VA RR&D Ctr Excellence, Decatur, GA USA

[2] Emory Univ, Sch Med, Dept Rehabil Med, Atlanta, GA USA

[3] Drexel Univ, Coll Med, Dept Neurol, Philadelphia, PA 19104 USA

[4] Univ Sci Philadelphia, Hlth Psychol Program, Philadelphia, PA USA

[5] Thomas Jefferson Univ, Jefferson Med Coll, Dept Psychiat & Human Behav, Philadelphia, PA 19107 USA

[6] Drexel Univ, Philadelphia, PA 19104 USA

[7] Georgia Gwinnett Coll, Lawrenceville, GA USA

来源：

JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY | 2010年 / 32卷 / 06期

关键词：

Small vessel ischemic disease; Sequential memory; Working memory; Mild cognitive impairment; Leukoaraiosis; MILD COGNITIVE IMPAIRMENT; MEDIAL PREFRONTAL CORTEX; VERBAL WORKING-MEMORY; RECOGNITION MEMORY; BINSWANGERS-DISEASE; PARKINSONS-DISEASE; BRAIN; LEUKOARAIOSIS; VALIDATION; MECHANISMS;

D O I：

10.1080/13803390903418918

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

Determining the order of events is essential for accurate memory recollection: an ability previously linked to both frontal and medial temporal functioning. Frontal-subcortical and medial temporal dysfunction typify vascular dementia (VaD) and Alzheimer's disease (AD), respectively. Therefore, we assessed patients' ordering abilities using a novel sequencing task that progressively increased memory load. VaD patients made more errors and selected more previously encountered stimuli than did AD. Curve analysis revealed a general decline in ordering for VaD whereas error production in AD is more dependent on memory load. These findings generally support the role of frontal-subcortical functioning in temporal order memory.

引用

页码：645 / 654

页数：10

共 66 条

[1] Nonpharmacological cognitive interventions in aging and dementia [J].

Acevedo, Amarilis ;

Loewenstein, David A. .

JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY, 2007, 20 (04) :239-249

[2]

[Anonymous], 1981, Wechsler Adult Intelligence Scale-Revised

[3] Executive functions in multiple sclerosis: An analysis of temporal ordering, semantic encoding, and planning abilities [J].

Arnett, PA ;

Rao, SM ;

Grafman, J ;

Bernardin, L ;

Luchetta, T ;

Binder, JR ;

Lobeck, L .

NEUROPSYCHOLOGY, 1997, 11 (04) :535-544

[4] The contribution of medial temporal lobe atrophy and vascular pathology to cognitive impairment in vascular dementia [J].

Bastos-Leite, Antonio J. ;

van der Flier, Wiesje M. ;

van Straaten, Elisabeth ;

Staekenborg, Salka S. ;

Scheltens, Philip ;

Barkhof, Frederik .

STROKE, 2007, 38 (12) :3182-3185

[5]

Becker L., 1998, Effect size calculators. Measures of effect size -Strength of association

[6]

Braak E, 1999, EUR ARCH PSY CLIN N, V249, P14

[7] Brain regions differentially involved in remembering what and when: a PET study [J].

Cabeza, R ;

Mangels, J ;

Nyberg, L ;

Habib, R ;

Houle, S ;

McIntosh, AR ;

Tulving, E .

NEURON, 1997, 19 (04) :863-870

[8] Functional neuroimaging of autobiographical memory [J].

Cabeza, Roberto ;

St Jacques, Peggy .

TRENDS IN COGNITIVE SCIENCES, 2007, 11 (05) :219-227

[9] Frontal impairment in subcortical ischemic vascular dementia in comparison to Alzheimer's disease [J].

Cannatà, AP ;

Alberoni, M ;

Franceschi, M ;

Mariani, C .

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 2002, 13 (02) :101-111

[10]

Capizzano AA, 2000, AM J NEURORADIOL, V21, P621

← 1 2 3 4 5 6 7 →