Satellite Sign: A Poor Outcome Predictor in Intracerebral Hemorrhage

被引：73

作者：

Shimoda, Yoshiteru ^{[1
,3
]}

Ohtomo, Satoru ^{[1
]}

Arai, Hiroaki ^{[1
]}

Okada, Ken ^{[2
]}

Tominaga, Teiji ^{[3
]}

机构：

[1] South Miyagi Med Ctr, Dept Neurosurg, 38-1 Azanishi, Ogawara, Miyagi 9891253, Japan

[2] South Miyagi Med Ctr, Dept Radiol, Ogawara, Miyagi, Japan

[3] Tohoku Univ, Grad Sch Med, Dept Neurosurg, Sendai, Miyagi, Japan

来源：

CEREBROVASCULAR DISEASES | 2017年 / 44卷 / 3-4期

关键词：

Intracerebral hemorrhage; Computed tomography; Cerebrovascular disease; Stroke; ANGIOGRAPHY SPOT SIGN; COMPUTED-TOMOGRAPHY; HEMATOMA GROWTH; BLOOD; DENSITY; INJURY; STROKE; VOLUME; SHAPE; MRI;

D O I：

10.1159/000477179

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: The presence of high-density starry dots around the intracerebral hemorrhage (ICH), which we termed as a satellite sign, is occasionally observed in CT. The relationship between ICH with a satellite sign and its functional outcome has not been identified. This study aimed to determine whether the presence of a satellite sign could be an independent prognostic factor for patients with ICH. Methods: Patients with acute spontaneous ICH were retrospectively identified and their initial CT scans were reviewed. A satellite sign was defined as scattered high-density lesions completely separate from the main hemorrhage in at least the single axial slice. Functional outcome was evaluated using the modified Rankin Scale (mRS) at discharge. Poor functional outcome was defined as mRS scores of 3-6. Univariate and multivariate logistic regression analyses were applied to assess the presence of a satellite sign and its association with poor functional outcome. Results: A total of 241 patients with ICH were enrolled in the study. Of these, 98 (40.7%) had a satellite sign. Patients with a satellite sign had a significantly higher rate of poor functional outcome (95.9%) than those without a satellite sign (55.9%, p < 0.0001). Multivariate logistic regression analysis revealed that higher age (OR 1.06; 95% CI 1.03-1.10; p = 0.00016), large hemorrhage size (OR 1.06; 95% CI 1.03-1.11; p = 0.00015), and ICH with a satellite sign (OR 13.5; 95% CI 4.42-53.4; p < 0.0001) were significantly related to poor outcome. A satellite sign was significantly related with higher systolic blood pressure (p = 0.0014), higher diastolic blood pressure (p = 0.0117), shorter activated partial thromboplastin time (p = 0.0427), higher rate of intraventricular bleeding (p < 0.0001), and larger main hemorrhage (p < 0.0001). Conclusions: The presence of a satellite sign in the initial CT scan is associated with a significantly worse functional outcome in ICH patients. (C) 2017 S. Karger AG, Basel

引用

页码：105 / 112

页数：8

共 32 条

[1] Density and Shape as CT Predictors of Intracerebral Hemorrhage Growth [J].

Barras, Christen D. ;

Tress, Brian M. ;

Christensen, Soren ;

MacGregor, Lachlan ;

Collins, Marnie ;

Desmond, Patricia M. ;

Skolnick, Brett E. ;

Mayer, Stephan A. ;

Broderick, Joseph P. ;

Diringer, Michael N. ;

Steiner, Thorsten ;

Davis, Stephen M. .

STROKE, 2009, 40 (04) :1325-1331

[2] Noncontrast Computed Tomography Hypodensities Predict Poor Outcome in Intracerebral Hemorrhage Patients [J].

Boulouis, Gregoire ;

Morotti, Andrea ;

Brouwers, H. Bart ;

Charidimou, Andreas ;

Jessel, Michael J. ;

Auriel, Eitan ;

Pontes-Neto, Octavio ;

Ayres, Alison ;

Vashkevich, Anastasia ;

Schwab, Kristin M. ;

Rosand, Jonathan ;

Viswanathan, Anand ;

Gurol, Mahmut E. ;

Greenberg, Steven M. ;

Goldstein, Joshua N. .

STROKE, 2016, 47 (10) :2511-2516

[3] Early hemorrhage growth in patients with intracerebral hemorrhage [J].

Brott, T ;

Broderick, J ;

Kothari, R ;

Barsan, W ;

Tomsick, T ;

Sauerbeck, L ;

Spilker, J ;

Duldner, J ;

Khoury, J .

STROKE, 1997, 28 (01) :1-5

[4] CT angiography spot sign in intracerebral hemorrhage predicts active bleeding during surgery [J].

Brouwers, H. Bart ;

Raffeld, Miriam R. ;

van Nieuwenhuizen, Koen M. ;

Falcone, Guido J. ;

Ayres, Alison M. ;

McNamara, Kristen A. ;

Schwab, Kristin ;

Romero, Javier M. ;

Velthuis, Birgitta K. ;

Viswanathan, Anand ;

Greenberg, Steven M. ;

Ogilvy, Christopher S. ;

van der Zwan, Albert ;

Rinkel, Gabriel J. E. ;

Goldstein, Joshua N. ;

Klijn, Catharina J. M. ;

Rosand, Jonathan .

NEUROLOGY, 2014, 83 (10) :883-889

[5] Perihematomal edema in primary intracerebral hemorrhage is plasma derived [J].

Butcher, KS ;

Baird, T ;

MacGregor, L ;

Desmond, P ;

Tress, B ;

Davis, S .

STROKE, 2004, 35 (08) :1879-1885

[6]

CAHILL DW, 1982, CLIN NEUR, V29, P722

[7] Subarachnoid Extension of Intracerebral Hemorrhage and 90-Day Outcomes in INTERACT2 [J].

Chen, Guofang ;

Arima, Hisatomi ;

Wu, Guojun ;

Heeley, Emma ;

Delcourt, Candice ;

Zhang, Peiying ;

Rabinstein, Alejandro A. ;

Robinson, Thompson ;

Stapf, Christian ;

Huang, Yining ;

Song, Lili ;

Yang, Jie ;

Wang, Xia ;

Li, Qiang ;

Chen, Xiaoying ;

Chalmers, John ;

Anderson, Craig .

STROKE, 2014, 45 (01) :258-260

[8] Multiple Simultaneous Spontaneous Intracerebral Hemorrhages: A Rare Entity [J].

Chen, Yaohua ;

Henon, Hilde ;

Bombois, Stephanie ;

Pasquier, Florence ;

Cordonnier, Charlotte .

CEREBROVASCULAR DISEASES, 2016, 41 (1-2) :74-79

[9] Significance of Hematoma Shape and Density in Intracerebral Hemorrhage The Intensive Blood Pressure Reduction in Acute Intracerebral Hemorrhage Trial Study [J].

Delcourt, Candice ;

Zhang, Shihong ;

Arima, Hisatomi ;

Sato, Shoichiro ;

Salman, Rustam Al-Shahi ;

Wang, Xia ;

Davies, Leo ;

Stapf, Christian ;

Robinson, Thompson ;

Lavados, Pablo M. ;

Chalmers, John ;

Heeley, Emma ;

Liu, Ming ;

Lindley, Richard I. ;

Anderson, Craig S. .

STROKE, 2016, 47 (05) :1227-1232

[10] Hydrocephalus: A previously unrecognized predictor of poor outcome from supratentorial intracerebral hemorrhage [J].

Diringer, MN ;

Edwards, DF ;

Zazulia, AR .

STROKE, 1998, 29 (07) :1352-1357

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