Synthesis of new diarylmethanes on the basis of resorcinol derivatives and amino acetals containing an aminoethylidenebisphosphonate fragment

被引：2
作者：
Vagapova, L. I. [1 ]
Makhrus, E. M. [2 ]
Burilov, A. R. [1 ]
Pudovik, M. A. [1 ]
机构：
[1] Russian Acad Sci, Kazan Res Ctr, Arbuzov Inst Organ & Phys Chem, Ul Akad Arbuzova 8, Kazan 420088, Tatarstan, Russia
[2] Kazan Natl Res Technol Univ, Kazan, Tatarstan, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2017年 / 87卷 / 09期
基金：
俄罗斯基础研究基金会;
关键词：
ethenylidenebisphosphonate; aminoacetals; Michael reaction; bisphosphonic acids; condensation; resorcinol; IN-VITRO; BISPHOSPHONATES; INHIBITORS; ACIDS; VIVO;
D O I：
10.1134/S1070363217090316
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
New ethylenebisphosphorylated alpha-amino acetals were synthesized by the reaction of aminoacetaldehyde dimethyl acetal with ethenylidenebisphosphonates (Michael reaction). It was found that the synthesized compounds react with 2-methylresorcinol and resorcinol in the presence of HCl to form previously unknown diarylalkylammonium salts containing ethylidenebisphosphonate groups.
引用
收藏
页码：2103 / 2106
页数：4
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