Increasing solubility of red bell pepper carotenoids by complexation with 2-hydroxypropyl-β-cyclodextrin

被引:42
作者
Petito, Nicolly de Lima [1 ]
Dias, Daiana da Silva [2 ]
Costa, Valeria Goncalves [3 ]
Falcao, Deborah Quintanilha [1 ]
de Lima Araujo, Katia Gome [1 ]
机构
[1] Univ Fed Fluminense, Fac Farm, Programa Posgrad Ciencias Aplicadas & Prod Saude, Rua Doutor Mario Viana 523, BR-24241000 Niteroi, RJ, Brazil
[2] Univ Fed Fluminense, Fac Nutr, Rua Mario Santos Braga 30,Campus Valonguinho, BR-24020140 Niteroi, RJ, Brazil
[3] Inst Nacl Tecnol, Saude, Ave Venezuela 82, BR-20081312 Rio De Janeiro, Brazil
关键词
Red bell pepper; 2-Hydroxypropyl-beta-cyclodextrin; Molecular inclusion; Carotenoids; HYDROXYPROPYL-BETA-CYCLODEXTRIN; INCLUSION COMPLEX; CAPSICUM-ANNUUM; STABILITY; ASTAXANTHIN; PIGMENTS; SYSTEM; TOOL; L;
D O I
10.1016/j.foodchem.2016.03.122
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Red bell pepper carotenoids were complexed with 2-hydroxypropyl-beta-cyclodextrin (2-HPbCD) in different mass ratios (1:4, 1:6, 1:8 and 1:10) through ultrasonic homogenization in order to increase carotenoid solubility and their use as natural pigment in food. Inclusion complexes, red bell pepper extract and physical mixtures were analyzed by DSC, FT-IR, H-1 NMR and DLS. Solubility assay was performed to identify the effect of complexation on the solubility of carotenoids. From characterization assays, results showed that inclusion process occurred for all tested ratios. Results for water solubility assays demonstrated clear differences between solubility index of inclusion complexes (8.06 +/- 2.59-16.55 +/- 4.40 mg/mL) and physical mixtures (3.53 +/- 1.44-7.3 +/- 1.88 mg/mL), while carotenoid extract was no water soluble, as expected. These results indicated that molecular inclusion of carotenoids in 2-HPbCD was efficient to enhance their solubility in water, enabling application of red bell pepper carotenoid as natural pigment and/or bioactive substances in food. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码:124 / 131
页数:8
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