Synchrotron crystallography

被引:98
作者
Hendrickson, WA [1 ]
机构
[1] Columbia Univ, Howard Hughes Med Inst, Dept Biochem & Mol Biophys, New York, NY 10032 USA
关键词
D O I
10.1016/S0968-0004(00)01721-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The past decade has seen an explosive growth in atomic-level structures determined by X-ray crystallography. Synchrotron radiation and a number of technical advances related quite directly to its development have fueled this growth. With the most recent advances coming to be used collectively and new resources being built, the foundation is laid for a dramatic further expansion of synchrotron crystallography in the next decade. Both the high-throughput applications of structural genomics and also the challenging studies of macromolecular machinery are expected to flourish.
引用
收藏
页码:637 / 643
页数:7
相关论文
共 40 条
  • [21] Strategies for macromolecular synchrotron crystallography
    Minor, W
    Tomchick, DR
    Otwinowski, Z
    [J]. STRUCTURE, 2000, 8 (05) : R105 - R110
  • [22] Potential for biomolecular imaging with femtosecond X-ray pulses
    Neutze, R
    Wouts, R
    van der Spoel, D
    Weckert, E
    Hajdu, J
    [J]. NATURE, 2000, 406 (6797) : 752 - 757
  • [23] Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA
    Obmolova, G
    Ban, C
    Hsieh, P
    Yang, W
    [J]. NATURE, 2000, 407 (6805) : 703 - 710
  • [24] Crystal structure of rhodopsin: A G protein-coupled receptor
    Palczewski, K
    Kumasaka, T
    Hori, T
    Behnke, CA
    Motoshima, H
    Fox, BA
    Le Trong, I
    Teller, DC
    Okada, T
    Stenkamp, RE
    Yamamoto, M
    Miyano, M
    [J]. SCIENCE, 2000, 289 (5480) : 739 - 745
  • [25] USE OF SYNCHROTRON ORBIT-RADIATION IN X-RAY PHYSICS
    PARRATT, LG
    [J]. REVIEW OF SCIENTIFIC INSTRUMENTS, 1959, 30 (04) : 297 - 299
  • [26] X-ray structure of bacteriorhodopsin at 2.5 angstroms from microcrystals grown in lipidic cubic phases
    PebayPeyroula, E
    Rummel, G
    Rosenbusch, JP
    Landau, EM
    [J]. SCIENCE, 1997, 277 (5332) : 1676 - 1681
  • [27] Automated protein model building combined with iterative structure refinement
    Perrakis, A
    Morris, R
    Lamzin, VS
    [J]. NATURE STRUCTURAL BIOLOGY, 1999, 6 (05) : 458 - 463
  • [28] APPLICATIONS OF SYNCHROTRON RADIATION TO PROTEIN CRYSTALLOGRAPHY - PRELIMINARY RESULTS
    PHILLIPS, JC
    WLODAWER, A
    YEVITZ, MM
    HODGSON, KO
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (01) : 128 - 132
  • [29] Structure of the reovirus core at 3.6 Å resolution
    Reinisch, KM
    Nibert, M
    Harrison, SC
    [J]. NATURE, 2000, 404 (6781) : 960 - 967
  • [30] Laue crystallography: coming of age
    Ren, Z
    Bourgeois, D
    Helliwell, JR
    Moffat, K
    Srajer, V
    Stoddard, BL
    [J]. JOURNAL OF SYNCHROTRON RADIATION, 1999, 6 : 891 - 917