A red-emitting fluorescent probe for biothiols detection with a large Stokes shift

被引：23

作者：

Qi, Fengpei ^{[1
,2
]}

Liu, Xingjiang ^{[1
]}

Yang, Lei ^{[1
]}

Yang, Liu ^{[1
]}

Chen, Wenqiang ^{[1
]}

Song, Xiangzhi ^{[1
,3
,4
]}

机构：

[1] Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China

[2] Hunan City Univ, Dept Chem & Environm Engn, Yiyang 413000, Hunan, Peoples R China

[3] Cent S Univ, State Key Lab Powder Met, Changsha 410083, Hunan, Peoples R China

[4] Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Liaoning, Peoples R China

来源：

TETRAHEDRON | 2016年 / 72卷 / 44期

关键词：

Biothiols; Fluorescent probe; Selectivity; Detection limit; Calorimetric; THIOL PROBE; RISK FACTOR; GLUTATHIONE; HOMOCYSTEINE; CYSTEINE; DISEASE; TISSUES; AMINOTHIOLS; SENSOR; CELLS;

D O I：

10.1016/j.tet.2016.08.020

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly selective red-emitting fluorescent probe for biothiols detection was developed. The addition of biothiols to the solution of this probe, 1, resulted in a strong red fluorescence with an obvious color change from red to claybank. This colorimetric and fluorescent dual probe exhibited a low detection limit (15 nM) and a large Stokes shift (147 nm) in detecting biothiols. Importantly, the utility of this probe for sensing intracellular thiols was successfully demonstrated in living HNE-2 cells. (C) 2016 Published by Elsevier Ltd.

引用

页码：6909 / 6913

页数：5

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