Polyoxygenated ergostane-type sterols from the liquid culture of Ganoderma applanatum

被引：23

作者：

Lee, So Young ^{[1
]}

Kim, Ju Sun ^{[1
]}

Lee, Sanghyun ^{[2
]}

Kang, Sam Sik ^{[1
]}

机构：

[1] Seoul Natl Univ, Coll Pharm, Inst Nat Prod Res, Seoul 151742, South Korea

[2] Chung Ang Univ, Dept Appl Plant Sci, Anseong 456756, South Korea

来源：

NATURAL PRODUCT RESEARCH | 2011年 / 25卷 / 14期

关键词：

Ganoderma applanatum; Polyporaceae; polyoxygenated ergostane; 3; beta; 5; alpha; 6; 8; 14; alpha-pentahydroxy-(22E; 24R)-ergost-22-en-7-one; liquid culture; FRUITING BODIES; ALDOSE REDUCTASE; LANOSTANE TRITERPENOIDS; NATURAL-PRODUCTS; CONSTITUENTS; POLYSACCHARIDES; LINGZHI; SPONGE; ACIDS;

D O I：

10.1080/14786419.2010.503190

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A new polyoxygenated ergostane-type sterol, 3 beta,5 alpha,6 beta,8 beta,14 alpha-pentahydroxy-(22E,24R)-ergost-22-en-7-one (1), has been isolated from the liquid culture of the basidiomycete Ganoderma applanatum together with four known sterols, 3 beta,5 alpha,9 alpha-trihydroxy-(22E,24R)-ergosta-7,22-dien-6-one (2), ergosterol peroxide (3), 6-dehydrocerevisterol (4) and cerevisterol (5). Two of these sterols (2, 4) are reported to have been isolated from this species for the first time. The structures of these compounds were determined by chemical and spectroscopic analyses, including 1D- and 2D-NMR, as well as by comparison of their spectroscopic data with those reported in the literature.

引用

页码：1304 / 1311

页数：8

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