Case Report: IgA Nephropathy in a Patient With Anti-Transcription Intermediary Factor-1γ Antibody-Positive Dermatomyositis

被引：3
作者：
Zhang, Suo [1 ,2 ]
Chen, Yu-Lan [1 ]
Liu, Cui-Lian [1 ]
Xie, Jing-Yi [1 ]
Sun, Bao-Dong [1 ]
Liu, Dong-Zhou [1 ]
机构：
[1] Southern Univ Sci & Technol, Affiliated Hosp 1, Dept Rheumatol & Immunol, Jinan Univ,Clin Med Coll 2,Shenzhen Peoples Hosp, Shenzhen, Peoples R China
[2] Shenzhen Second Peoples Hosp, Dept Rheumatol & Immunol, Shenzhen, Peoples R China
来源：
FRONTIERS IN IMMUNOLOGY | 2022年 / 13卷
基金：
中国国家自然科学基金;
关键词：
IgA nephropathy; systemic autoimmune myopathies; dermatomyositis; anti- transcription intermediary factor-1 gamma antibody; dermatomyositis-specific antibodies; RENAL INVOLVEMENT; POLYMYOSITIS; AUTOANTIBODIES; SPECTRUM; GLOMERULONEPHRITIS; CLASSIFICATION; DISEASE; RISK; LOCI;
D O I：
10.3389/fimmu.2022.757802
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis characterized by IgA deposits in the mesangial area of glomeruli. Connective tissue disorders are some of the most frequent causes of secondary IgAN. Nevertheless, IgAN rarely occurs in systemic autoimmune myopathies (SAMs). The present case study reports on a 58-year-old patient with dermatomyositis with positive anti-transcription intermediary factor (TIF)-1 gamma antibodies who was diagnosed with IgAN during standard immunosuppressive therapy. Moreover, we have made a systematic review regarding the association of SAMs and IgAN. To the best of the authors' knowledge, this is the first case study describing a patient with anti-TIF1 gamma antibody-positive dermatomyositis who developed IgAN, which demonstrates a potential relationship between anti-TIF1 gamma-positive dermatomyositis and IgAN. It is important for clinicians to be aware of the possibility of renal involvement in patients with SAMs, even in those with anti-TIF1 gamma-positive dermatomyositis.
引用
收藏
页数：7
相关论文
共 40 条
[1]   The Histopathologic Spectrum of Kidney Biopsies in Patients with Inflammatory Bowel Disease [J].
Ambruzs, Josephine M. ;
Walker, Patrick D. ;
Larsen, Christopher P. .
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2014, 9 (02) :265-270
[2]   POLYMYOSITIS AND DERMATOMYOSITIS .1. [J].
BOHAN, A ;
PETER, JB .
NEW ENGLAND JOURNAL OF MEDICINE, 1975, 292 (07) :344-347
[3]   Spondyloarthritis-Associated IgA Nephropathy [J].
Champtiaux, Nicolas ;
Liote, Frederic ;
El Karoui, Khalil ;
Vigneau, Cecile ;
Miceli, Corinne ;
Cornec-Le Gall, Emilie ;
Remy, Philippe ;
Choukroun, Gabriel ;
Fakhouri, Fadi ;
Garrouste, Cyril ;
Veillon, Laurent ;
Pillebout, Evangeline ;
Lobbedez, Thierry ;
Vuiblet, Vincent ;
Wynckel, Alain ;
Guincestre, Thomas ;
Toussirot, Eric ;
Thervet, Eric ;
Rabant, Marion ;
Karras, Alexandre .
KIDNEY INTERNATIONAL REPORTS, 2020, 5 (06) :813-820
[4]   The Role of Immune Modulation in Pathogenesis of IgA Nephropathy [J].
Chang, Sheng ;
Li, Xiao-Kang .
FRONTIERS IN MEDICINE, 2020, 7
[5]   IgA Nephropathy in Two Patients with Sjogren's Syndrome: One with Concomitant Autoimmune Hepatitis [J].
Chen, Yizhi ;
Zhao, Xuezhi ;
Tang, Dan ;
Xu, Chenggang ;
Sun, Linlin ;
Sun, Lijun ;
Wu, Jun ;
Mei, Changlin .
INTERNAL MEDICINE, 2010, 49 (01) :37-43
[6]   Paraneoplastic Polymyositis Associated with Crescentic Glomerulonephritis [J].
Chiu, Kuan-Chi ;
Tsai, Tsung-Chang ;
Lin, Wei-Tung ;
Lee, Wei-Jen ;
Su, Ching-Chyuan ;
Chen, Chen-Yin .
RENAL FAILURE, 2008, 30 (09) :939-942
[7]   Immunoglobulin A nephropathy associated with juvenile dermatomyositis [J].
Civilibal, Mahmut ;
Duru, Nilgun Selcuk ;
Ozagari, Aysim ;
Durali, Kemal ;
Elevli, Murat .
PEDIATRIC NEPHROLOGY, 2009, 24 (10) :2073-2075
[8]   The Spectrum of Renal Involvement in Patients With Inflammatory Myopathies [J].
Couvrat-Desvergnes, Gregoire ;
Masseau, Agathe ;
Benveniste, Olivier ;
Bruel, Alexandra ;
Hervier, Baptiste ;
Mussini, Jean-Marie ;
Buob, David ;
Hachulla, Eric ;
Remy, Philippe ;
Azar, Raymond ;
Mac Namara, Evelyne ;
MacGregor, Brigitte ;
Daniel, Laurent ;
Lacraz, Adeline ;
De Broucker, Thomas ;
Rouvier, Philippe ;
Carli, Philippe ;
Laville, Maurice ;
Dantan, Etienne ;
Hamidou, Mohamed ;
Moreau, Anne ;
Fakhouri, Fadi .
MEDICINE, 2014, 93 (01) :33-41
[9]   Renal Involvement in Idiopathic Inflammatory Myopathies [J].
Cucchiari, David ;
Angelini, Claudio .
CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, 2017, 52 (01) :99-107
[10]   Anti-TIF1-γ autoantibodies: warning lights of a tumour autoantigen [J].
De Vooght, Julie ;
Vulsteke, Jean-Baptiste ;
De Haes, Petra ;
Bossuyt, Xavier ;
Lories, Rik ;
De Langhe, Ellen .
RHEUMATOLOGY, 2020, 59 (03) :469-477
1234