L-Asparaginase as morpheein: A potential drug target

被引:0
作者
Vimal, Archana [1 ]
Kumar, Awanish [1 ]
机构
[1] NIT, Dept Biotechnol, Raipur 492010, Chhattisgarh, India
关键词
L-Asparaginase; Morpheein; Allosterism; Drug target; ALLOSTERIC REGULATION;
D O I
10.1016/j.phrs.2016.05.011
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:101 / 101
页数:1
相关论文
共 5 条
  • [1] Mycobacterium tuberculosis Exploits Asparagine to Assimilate Nitrogen and Resist Acid Stress during Infection
    Gouzy, Alexandre
    Larrouy-Maumus, Gerald
    Bottai, Daria
    Levillain, Florence
    Dumas, Alexia
    Wallach, Joshua B.
    Caire-Brandli, Irene
    de Chastellier, Chantal
    Wu, Ting-Di
    Poincloux, Renaud
    Brosch, Roland
    Guerquin-Kern, Jean-Luc
    Schnappinger, Dirk
    de Carvalho, Luiz Pedro Sorio
    Poquet, Yannick
    Neyrolles, Olivier
    [J]. PLOS PATHOGENS, 2014, 10 (02)
  • [2] Morpheeins - a new structural paradigm for allosteric regulation
    Jaffe, EK
    [J]. TRENDS IN BIOCHEMICAL SCIENCES, 2005, 30 (09) : 490 - 497
  • [3] L-ASPARAGINASE ACTIVITY IN LEPTOSPHAERIA-MICHOTII - ISOLATION AND PROPERTIES OF 2 FORMS OF THE ENZYME
    JEREBZOFFQUINTIN, S
    JEREBZOFF, S
    [J]. PHYSIOLOGIA PLANTARUM, 1985, 64 (01) : 74 - 80
  • [4] Asparagine deprivation mediated by Salmonella asparaginase causes suppression of activation-induced T cell metabolic reprogramming
    Torres, AnnMarie
    Luke, Joanna D.
    Kullas, Amy L.
    Kapilashrami, Kanishk
    Botbol, Yair
    Koller, Antonius
    Tonge, Peter J.
    Chen, Emily I.
    Macian, Fernando
    van der Velden, Adrianus W. M.
    [J]. JOURNAL OF LEUKOCYTE BIOLOGY, 2016, 99 (02) : 387 - 398
  • [5] Crystal structure and allosteric regulation of the cytoplasmic Escherichia coli L-asparaginase I
    Yun, Mi-Kyung
    Nourse, Amanda
    White, Stephen W.
    Rock, Charles O.
    Heath, Richard J.
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 2007, 369 (03) : 794 - 811