Electrophilic cyclization of 4-thio-but-2-yn-1-ols via 1,2-migration of the thio group: efficient synthesis of 2,4-dihalo-3-thio-substituted furans

被引：14
作者：
Zhou, Hongwei [1 ]
Yao, Jinzhong [1 ]
Liu, Guoliang [1 ]
机构：
[1] Zhejiang Univ, Dept Chem, Hangzhou 310028, Zhejiang, Peoples R China
来源：
TETRAHEDRON LETTERS | 2008年 / 49卷 / 02期
基金：
中国国家自然科学基金;
关键词：
electrophilic cyclization; 1,2-migration of thio group; 2,4-dihalo-3-thio-furan; 4-thio-but-2-yn-1-ol;
D O I：
10.1016/j.tetlet.2007.11.092
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A facile and efficient method for the synthesis of 2,4-dihalo-3-thio-furans via the electrophilic cyclization and 1,2-migration of the thio group of 4-thio-but-2-yn-1-ols was developed. As a result of the ready availability of starting materials and the simple and convenient operation, this synthetic route would have potential utility in organic synthesis. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码：226 / 228
页数：3
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