Management of hyperthyroidism due to Graves' disease: frequently asked questions and answers (if any)

被引：53
|
作者：
Bartalena, L. [1 ]
Chiovato, L. [2 ,3 ]
Vitti, P. [4 ]
机构：
[1] Univ Insubria, ASST Sette Laghi, Dept Clin & Expt Med, Endocrine Unit,Osped Circolo, Viale Borri 57, Varese, Italy
[2] Fdn Salvatore Maugeri, Pavia, Italy
[3] Univ Pavia, Pavia, Italy
[4] Univ Pisa, Dept Clin & Expt Med, Pisa, Italy
来源：
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION | 2016年 / 39卷 / 10期
关键词：
Graves' disease; Hyperthyroidism; Graves' orbitopathy; Thionamides; Methimazole; Propylthiouracil; Radioiodine; Thyroidectomy; Pregnancy; Childhood; Alemtuzumab; Agranulocytosis; AMERICAN THYROID ASSOCIATION; DRUG-INDUCED AGRANULOCYTOSIS; SHARED DECISION-MAKING; ANTITHYROID DRUGS; RADIOIODINE TREATMENT; RADIOACTIVE IODINE; IMMUNE RECONSTITUTION; CARBIMAZOLE EMBRYOPATHY; RETROSPECTIVE ANALYSIS; MULTIPLE-SCLEROSIS;
D O I：
10.1007/s40618-016-0505-x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Graves' disease is the most common cause of hyperthyroidism in iodine-replete areas. Although progress has been made in our understanding of the pathogenesis of the disease, no treatment targeting pathogenic mechanisms of the disease is presently available. Therapies for Graves' hyperthyroidism are largely imperfect because they are bound to either a high rate of relapsing hyperthyroidism (antithyroid drugs) or lifelong hypothyroidism (radioiodine treatment or thyroidectomy). Aim of the present article is to offer a practical guidance to the reader by providing evidence-based answers to frequently asked questions in clinical practice.
引用
收藏
页码：1105 / 1114
页数：10
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