A high-strength, toughness, self-recovery hydrogel for potential osteochondral repair

被引：2
|
作者：
Gang, Fangli [1 ]
机构：
[1] Xinzhou Teachers Univ, Dept Biol, Xinzhou 034000, Shanxi, Peoples R China
来源：
MATERIALS LETTERS | 2022年 / 307卷
关键词：
Biomaterials; Hydrogels; Nanocomposites; Porous materials;
D O I：
10.1016/j.matlet.2021.131064
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Many load-bearing tissues, such as osteochondral and meniscus, show high strength, toughness and rapid recovery. However, incorporating these mechanical properties into similar biomimetic synthetic biomaterials is a fundamental challenge. Here, we demonstrate a strong, tough and self-recovery hydrogel employing double network (DN) strategy and multiple dynamic interactions (such as metal coordination, hydrogen bond, etc.). The hybrid DN hydrogel exhibited remarkable compressive strength of 3.74 MPa, elongation of 418.92%, fracture energy of 9.41 kJ.m(-2), excellent cytocompatibility and self-recovery, so it has a great application prospect in osteochondral repair.
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页数：4
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