Physicochemical and Biological Properties of Oxovanadium(IV), Cobalt(II) and Nickel(II) Complexes with Oxydiacetate Anions

被引：18
|
作者：
Wyrzykowski, Dariusz [1 ]
Kloska, Anna [2 ]
Pranczk, Joanna [1 ]
Szczepanska, Aneta [2 ]
Tesmar, Aleksandra [1 ]
Jacewicz, Dagmara [1 ]
Pilarski, Boguslaw [3 ]
Chmurzynski, Lech [1 ]
机构：
[1] Univ Gdansk, Fac Chem, PL-80308 Gdansk, Poland
[2] Univ Gdansk, Fac Biol, PL-80308 Gdansk, Poland
[3] Cerko Sp Zoo SP K, PL-81451 Gdynia, Poland
来源：
BIOLOGICAL TRACE ELEMENT RESEARCH | 2015年 / 164卷 / 01期
关键词：
Oxydiacetate complexes; Cytoprotective activity; Antimicrobial activity; Potentiometric titration; Conductometric titration; Stability constant; BINARY SOLVENT MIXTURES; DIMETHYLSULFOXIDE WATER MIXTURES; X-RAY CHARACTERIZATION; CRYSTAL-STRUCTURES; CONCENTRATION DEPENDENCE; ELECTROLYTE CONDUCTANCE; DIMETHYL-SULFOXIDE; PITTS TREATMENTS; METAL-COMPLEXES; FUOSS-ONSAGER;
D O I：
10.1007/s12011-014-0170-x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The potentiometric and conductometric titration methods have been used to characterize the stability of series of VO(IV)-, Co(II)- and Ni(II)-oxydiacetato complexes in DMSO-water solutions containing 0-50 % (v/v) DMSO. The influence of DMSO as a co-solvent on the stability of the complexes as well as the oxydiacetic acid was evaluated. Furthermore, the reactivity of the complexes towards superoxide free radicals was assessed by employing the nitro blue tetrazolium (NBT) assay. The biological properties of the complexes were investigated in relation to their cytoprotective activity against the oxidative damage generated exogenously by using hydrogen peroxide in the Human Dermal Fibroblasts adult (HDFa) cell line as well as to their antimicrobial activity against the bacteria (Bacillus subtilis, Escherichia coli, Enterococcus faecalis, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis). The relationship between physicochemical and biological properties of the complexes was discussed.
引用
收藏
页码：139 / 149
页数：11
相关论文
共 50 条
  • [31] Synthesis, Physicochemical, and Biological Studies of Complexes of 2-Aminobenzohydrazine with Co(II), Ni(II), Cu(II), and Zn(II) Chlorides
    Saeed-Ur-Rehman
    Ikram, Muhammad
    Rehman, Sadia
    Ullah, Farhat
    Akhtar, Gul
    SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY, 2010, 40 (10) : 847 - 854
  • [32] Synthesis, characterization, and biological activities of copper(II), zinc(II), iron(III), cobalt(III), and nickel(II) complexes of D-glucosamine
    Shen, HY
    Liang, SY
    Luo, ZF
    Zhang, XC
    Zhu, XD
    SYNTHESIS AND REACTIVITY IN INORGANIC AND METAL-ORGANIC CHEMISTRY, 2001, 31 (01): : 167 - 177
  • [33] Nickel (II) and Cobalt (II) Complexes of Some Amino Acid-based Surfactants with Antimicrobial Activity
    Varasteanu, Dana
    Chican, Irina
    Doncea, Sanda Maria
    Raut, Iuliana
    Calin, Mariana
    Jecu, Luiza
    REVISTA DE CHIMIE, 2019, 70 (02): : 361 - 364
  • [34] Synthesis, spectral, thermal and antimicrobial studies on cobalt(II), nickel(II), copper(II), zinc(II) and palladium(II) complexes containing thiosemicarbazone ligand
    El-Sawaf, Ayman K.
    El-Essawy, Farag
    Nassar, Amal A.
    El-Samanody, El-Sayed A.
    JOURNAL OF MOLECULAR STRUCTURE, 2018, 1157 : 381 - 394
  • [35] Synthesis, characterization and biological activity of complexes of 2-hydroxy-3,5-dimethylacetophenoneoxime (HDMAOX) with copper(II), cobalt(II), nickel(II) and palladium(II)
    Singh, Bibhesh K.
    Jetley, Umesh K.
    Sharma, Rakesh K.
    Garg, Bhagwan S.
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2007, 68 (01) : 63 - 73
  • [36] Copper(II), cobalt(II), manganese(II) and nickel(II) bis(hexafluoroacetylacetonate) complexes with N-vinylimidazole
    Smirnov, Vladimir I.
    Sinegovskaya, Lidiya M.
    Parshina, Lidiya N.
    Artem'ev, Alexander V.
    Sterkhova, Irina V.
    MENDELEEV COMMUNICATIONS, 2020, 30 (02) : 246 - 248
  • [37] Metalloantibiotics: Synthesis and antibacterial activity of cobalt(II), copper(II), nickel(II) and zinc(II) complexes of kefzol
    Chohan, ZH
    Supuran, CT
    Scozzafava, A
    JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2004, 19 (01) : 79 - 84
  • [38] Synthesis and characterization of copper(II), cobalt(II), nickel(II), and iron(III) complexes with two diamine Schiff bases and catalytic reactivity of a chiral diamine cobalt(II) complex
    Youssef, Nabil S.
    El-Zahany, Eman A.
    Barsoum, Barsoum N.
    El-Seidy, Ahmed M. A.
    TRANSITION METAL CHEMISTRY, 2009, 34 (08) : 905 - 914
  • [39] Precursor molecules for 1,2-diamidobenzene containing cobalt(ii), nickel(ii) and zinc(ii) complexes - synthesis and magnetic properties
    Hunger, David
    Suhr, Simon
    Bayer, Valentin
    Albold, Uta
    Frey, Wolfgang
    Sarkar, Biprajit
    van Slageren, Joris
    DALTON TRANSACTIONS, 2024, 53 (23) : 9852 - 9861
  • [40] Structural Variety of Cobalt(II), Nickel(II), Zinc(II), and Cadmium(II) Complexes with 4,4′-Azopyridine: Synthesis, Structure and Luminescence Properties
    Pladzyk, Agnieszka
    Ponikiewski, Lukasz
    Dolega, Anna
    Slowy, Klaudia
    Sokolowska, Agata
    Dziubinska, Katarzyna
    Hnatejko, Zbigniew
    CHEMISTRY-AN ASIAN JOURNAL, 2015, 10 (11) : 2388 - 2396
12345