Surgical resection of primary soft-tissue sarcoma - Incidence of residual tumour in 95 patients needing re-excision after local resection

被引:80
作者
Goodlad, JR [1 ]
Fletcher, CDM [1 ]
Smith, MA [1 ]
机构
[1] ST THOMAS HOSP, LONDON SE1 7EH, ENGLAND
来源
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME | 1996年 / 78B卷 / 04期
关键词
D O I
10.1302/0301-620X.78B4.0780658
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
We reviewed retrospectively 236 consecutive patients seen in our soft-tissue sarcoma clinic, Of these, 95 had had a primary soft-tissue sarcoma excised elsewhere, but with histologically inadequate resection margins, All these patients had a secondary and wider re-excision, The tissues removed at the secondary re-excision were examined histologically for the presence of residual tumour, Definite tumour tissue aas found in 29 of 55 lower-limb specimens, 16 of 25 upper-limb, 7 of 10 trunk and 4 of 5 head and neck specimens, In 31 cases some residual tumour was visible macroscopically, and in 56 of the 95 patients (59%) the primary tumour had been incompletely excised. Our results indicate that surgical assessment of the adequacy of excision is vers inaccurate and that most local recurrences are the consequence of inadequate primary surgery, The large number of patients who had inadequate initial treatment emphasises the need for a co-ordinated multidisciplinary approach to the management of patients with soft-tissue sarcoma.
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页码:658 / 661
页数:4
相关论文
共 19 条
  • [1] INFLUENCE OF LOCAL RECURRENCE ON SURVIVAL - A CONTROVERSY REVIEWED FROM THE PERSPECTIVE OF SOFT-TISSUE SARCOMA
    BARR, LC
    STOTTER, AT
    AHERN, RP
    [J]. BRITISH JOURNAL OF SURGERY, 1991, 78 (06) : 648 - 650
  • [2] THE SURGICAL MARGIN IN SOFT-TISSUE SARCOMA
    BELL, RS
    OSULLIVAN, B
    LIU, FF
    POWELL, J
    LANGER, F
    FORNASIER, VL
    CUMMINGS, B
    MICELI, PN
    HAWKINS, N
    QUIRT, I
    WARR, D
    [J]. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1989, 71A (03) : 370 - 375
  • [3] LOCALIZED OPERABLE SOFT-TISSUE SARCOMA OF THE UPPER EXTREMITY - PRESENTATION, MANAGEMENT, AND FACTORS AFFECTING LOCAL RECURRENCE IN 108 PATIENTS
    COLLIN, C
    HAJDU, SI
    GODBOLD, J
    FRIEDRICH, C
    BRENNAN, MF
    [J]. ANNALS OF SURGERY, 1987, 205 (04) : 331 - 339
  • [4] ENNEKING WF, 1981, CANCER, V47, P1005, DOI 10.1002/1097-0142(19810301)47:5<1005::AID-CNCR2820470532>3.0.CO
  • [5] 2-9
  • [6] GUSTAFSON P, 1991, CANCER, V67, P2083, DOI 10.1002/1097-0142(19910415)67:8<2083::AID-CNCR2820670813>3.0.CO
  • [7] 2-5
  • [8] GUSTAFSON P, 1994, ACTA ORTHOP SCAND, V65, P1
  • [9] SOFT-TISSUE SARCOMA SHOULD BE TREATED AT A TUMOR CENTER - A COMPARISON OF QUALITY OF SURGERY IN 375 PATIENTS
    GUSTAFSON, P
    DREINHOFER, KE
    RYDHOLM, A
    [J]. ACTA ORTHOPAEDICA SCANDINAVICA, 1994, 65 (01): : 47 - 50
  • [10] LIMITATIONS OF COMPUTED-TOMOGRAPHY FOLLOWING EXCISIONAL BIOPSY OF SOFT-TISSUE SARCOMAS
    HUDSON, TM
    SCHAKEL, M
    SPRINGFIELD, DS
    [J]. SKELETAL RADIOLOGY, 1985, 13 (01) : 49 - 54