Ictal Very Low Frequency Oscillation in Human Epilepsy Patients

被引：20

作者：

Ren, Liankun ^{[1
,2
]}

Terada, Kiyohito ^{[1
]}

Baba, Koichi ^{[3
]}

Usui, Naotaka ^{[3
]}

Umeoka, Shuichi ^{[3
]}

Usui, Keiko ^{[1
]}

Matsuda, Kazumi ^{[3
]}

Tottori, Takayasu ^{[3
]}

Nakamura, Fumihiro ^{[4
]}

Mihara, Tadahiro ^{[3
]}

Inoue, Yushi ^{[4
]}

机构：

[1] Shizuoka Inst Epilepsy & Neurol Disorders, Natl Epilepsy Ctr, Dept Neurol, Aoi Ku, Shizuoka 4208688, Japan

[2] China Japan Friendship Hosp, Dept Neurol, Beijing, Peoples R China

[3] Shizuoka Inst Epilepsy & Neurol Disorders, Natl Epilepsy Ctr, Dept Neurosurg, Aoi Ku, Shizuoka 4208688, Japan

[4] Shizuoka Inst Epilepsy & Neurol Disorders, Natl Epilepsy Ctr, Dept Psychiat, Aoi Ku, Shizuoka 4208688, Japan

来源：

ANNALS OF NEUROLOGY | 2011年 / 69卷 / 01期

关键词：

BRAIN; NEUROSCIENCE; SEIZURES; GLUTAMATE; CORTEX; GLIA;

D O I：

10.1002/ana.22158

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Using intracranial electroencephalographic recordings, we identified a distinct brain activity in 3 patients with refractory epilepsy characterized by very early occurrence from 8 minutes 10 seconds to 22 minutes 40 seconds prior to clinical seizure onset, periodical appearance of slow negative baseline shift, long interpeak interval of 40 to 120 seconds, and disappearance after clinical seizure. We named this activity "very low frequency oscillation" (VLFO), which reflected a dynamic process during the preictal state. This observation may render new insight into epileptogenesis and provide additional information concerning the epileptogenic zone as well as prediction of epileptic seizures.

引用

页码：201 / 206

页数：6

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