Toward a prostate cancer precision medicine

被引：8

作者：

Rubin, Mark A. ^{[1
,2
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,4
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机构：

[1] Weill Cornell Med Coll, Inst Precis Med, New York, NY 10065 USA

[2] New York Presbyterian Hosp, New York, NY USA

[3] Weill Cornell Med Coll, Dept Pathol & Lab Med, New York, NY USA

[4] Weill Cornell Med Coll, Dept Urol, New York, NY USA

[5] Weill Cornell Med Coll, Meyer Canc Ctr, New York, NY USA

来源：

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS | 2015年 / 33卷 / 02期

关键词：

Prostate cancer; Precision medicine; Biomarkers; Next generation sequencing;

D O I：

10.1016/j.urolonc.2014.10.011

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The promise of precision cancer medicine is that we will be able to pair clinical and genomic data to provide better and more efficient treatment for cancer care. Although the focus is on the optimal pairing of existing Food and Drug Administration approved drugs with the patient's tumor, precision medicine should also help determine a patient's risk for disease progression. Precision medicine will hopefully also lead to improved molecular biomarkers. The specific needs for predictive biomarkers vary significantly based on cancer type. The chief aim for prostate cancer. biomarker development is to help distinguish indolent from aggressive disease. (C) 2014 Elsevier Inc. All rights reserved.

引用

页码：73 / 74

页数：2

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