Mesenchymal stem cells for tissue engineering and regenerative medicine

被引:46
作者
Tae, Suk-Kee [1 ]
Lee, Seok-Hyn [1 ]
Park, Jae-Sik [1 ]
Im, Gun-Il [1 ]
机构
[1] Dongguk Univ, Int Hosp, Dept Orthopaed, Goyang, South Korea
关键词
D O I
10.1088/1748-6041/1/2/003
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Mesenchymal stem cells (MSCs) exist in bone marrow and other musculoskeletal tissues. These cells contribute to the homeostasis of musculoskeletal tissue as well as support for the growth and differentiation of primitive hemopoietic cells. Recent advancements in tissue engineering and regenerative medicine have highlighted MSCs as a potential source of cells which would differentiate to a variety of tissue tailored to individual needs. This paper briefly outlines the current status of MSCs, focusing on their biological characteristics and potential for clinical applications.
引用
收藏
页码:63 / 71
页数:9
相关论文
共 108 条
  • [1] Adult stem cell driven genesis of human-shaped articular condyle
    Alhadlaq, A
    Elisseeff, JH
    Hong, L
    Williams, CG
    Caplan, AI
    Sharma, B
    Kopher, RA
    Tomkoria, S
    Lennon, DP
    Lopez, A
    Mao, JJ
    [J]. ANNALS OF BIOMEDICAL ENGINEERING, 2004, 32 (07) : 911 - 923
  • [2] Tissue-engineered neogenesis of human-shaped mandibular condyle from rat mesenchymal stem cells
    Alhadlaq, A
    Mao, JJ
    [J]. JOURNAL OF DENTAL RESEARCH, 2003, 82 (12) : 951 - 956
  • [3] Cotransplantation of stroma results in enhancement of engraftment and early expression of donor hematopoietic stem cells in utero
    Almeida-Porada, G
    Flake, AW
    Glimp, HA
    Zanjani, ED
    [J]. EXPERIMENTAL HEMATOLOGY, 1999, 27 (10) : 1569 - 1575
  • [4] Cotransplantation of human stromal cell progenitors into preimmune fetal sheep results in early appearance of human donor cells in circulation and boosts cell levels in bone marrow at later time points after transplantation
    Almeida-Porada, G
    Porada, CD
    Tran, N
    Zanjani, ED
    [J]. BLOOD, 2000, 95 (11) : 3620 - 3627
  • [5] Heterogeneity in the progeny of single human muscle satellite cells
    Baroffio, A
    BochatonPiallat, ML
    Gabbiani, G
    Bader, CR
    [J]. DIFFERENTIATION, 1995, 59 (04) : 259 - 268
  • [6] Chondrogenic differentiation of mesenchymal stem cells from bone marrow: Differentiation-dependent gene expression of matrix components
    Barry, F
    Boynton, RE
    Liu, BS
    Murphy, JM
    [J]. EXPERIMENTAL CELL RESEARCH, 2001, 268 (02) : 189 - 200
  • [7] Dynamics of myoblast transplantation reveal a discrete minority of precursors with stem cell-like properties as the myogenic source
    Beauchamp, JR
    Morgan, JE
    Pagel, CN
    Partridge, TA
    [J]. JOURNAL OF CELL BIOLOGY, 1999, 144 (06) : 1113 - 1121
  • [8] Large scale recovery and characterization of stromal cell-associated primitive haemopoietic progenitor cells from filter-retained human bone marrow
    Blazsek, I
    Marsalet, BD
    Legras, S
    Marion, S
    Machover, D
    Misset, JL
    [J]. BONE MARROW TRANSPLANTATION, 1999, 23 (07) : 647 - 657
  • [9] Axis of evil: molecular mechanisms of cancer metastasis
    Bogenrieder, T
    Herlyn, M
    [J]. ONCOGENE, 2003, 22 (42) : 6524 - 6536
  • [10] Bruder SP, 1997, J CELL BIOCHEM, V64, P278, DOI 10.1002/(SICI)1097-4644(199702)64:2<278::AID-JCB11>3.0.CO