Polyhydroxyalkanoates as biomaterials

被引：54

作者：

Bhagyashri, S. ^{[1
]}

Gadgil, Thorat ^{[1
]}

Killi, Naresh ^{[1
]}

Rathna, Gundloori V. N. ^{[1
]}

机构：

[1] CSIR Natl Chem Lab, Polymer Sci & Engn Div, Dr Homi Bhabha Rd, Pune 411008, Maharashtra, India

来源：

MEDCHEMCOMM | 2017年 / 8卷 / 09期

关键词：

DRUG-DELIVERY SYSTEMS; IN-VITRO; BIOMEDICAL INVESTIGATIONS; POLY(ETHYLENE GLYCOL); POLY(ESTER URETHANE)S; MEDICAL APPLICATION; ANTIBIOTIC RELEASE; MOLECULAR-WEIGHT; PHA SCAFFOLDS; TISSUE;

D O I：

10.1039/c7md00252a

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Polyhydroxyalkanoates (PHAs) are biopolymers synthesized by bacteria under unbalanced growth conditions. These biopolymers are considered as potential biomaterials for future applications because they are biocompatible, biodegradable, and easy to produce and functionalize with strong mechanical strength. Currently, PHAs are being extensively innovated for biomedical applications due to their prerequisite properties. The wide range of biomedical applications includes drug delivery systems, implants, tissue engineering, scaffolds, artificial organ constructs, etc. In this article we review the utility of PHAs in various forms (bulk/nano) for biomedical applications so as to bring about the future vision for PHAs as biomaterials for the advancement of research and technology.

引用

页码：1774 / 1787

页数：14

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