Prevalence of antibodies to hepatitis E virus in residents of a district in Havana, Cuba

被引：12

作者：

Quintana, A

Sanchez, L

Larralde, O

Anderson, D

机构：

[1] Univ Saarland, Dept Physiol, D-66421 Homburg, Germany

[2] Inst Trop Med Medro Kouri, Havana, Cuba

[3] Univ Glasgow, Inst Biomed & Life Sci, Div Virol, Glasgow G12 8QQ, Lanark, Scotland

来源：

JOURNAL OF MEDICAL VIROLOGY | 2005年 / 76卷 / 01期

关键词：

hepatitis E virus; anti-HEV prevalence; Cuba;

D O I：

10.1002/jmv.20324

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A seroepidemiological study of hepatitis E virus (HEV) infection was conducted in a district of Havana, where hepatitis A virus (HAV) is considered endemic. The levels of anti-HEV antibodies were evaluated by enzyme-linked immunosorbent assay (ELISA) based on the recombinant protein GST-ORF2.1. Anti-HEV antibodies were detected in 11 of 209 (5.3%) of serum samples, compared to 71.3% for anti-HAV antibodies. No risk factors reported previously for HEV infection showed a significant association with the presence of anti-HEV antibodies., whereas anti-HAV antibodies were strongly associated with increasing age. HEV may be considered endemic in this area and is likely to have a significant clinical impact. (c) 2005 Wiley-Liss, Inc.

引用

页码：69 / 70

页数：2

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