Epicardial fat;
Computed tomography;
3D segmentation;
Deep learning;
3D U-Net;
Attention gate;
Deep supervision;
D O I:
10.7717/peerj-cs.806
中图分类号:
TP18 [人工智能理论];
学科分类号:
081104 ;
0812 ;
0835 ;
1405 ;
摘要:
Epicardial fat (ECF) is localized fat surrounding the heart muscle or myocardium and enclosed by the thin-layer pericardium membrane. Segmenting the ECF is one of the most difficult medical image segmentation tasks. Since the epicardial fat is infiltrated into the groove between cardiac chambers and is contiguous with cardiac muscle, segmentation requires location and voxel intensity. Recently, deep learning methods have been effectively used to solve medical image segmentation problems in several domains with state-of-the-art performance. This paper presents a novel approach to 3D segmentation of ECF by integrating attention gates and deep supervision into the 3D U-Net deep learning architecture. The proposed method shows significant improvement of the segmentation performance, when compared with standard 3D U-Net. The experiments show excellent performance on non-contrast CT datasets with average Dice scores of 90.06%. Transfer learning from a pre-trained model of a non-contrast CT to contrast-enhanced CT dataset was also performed. The segmentation accuracy on the contrast-enhanced CT dataset achieved a Dice score of 88.16%.
机构:
Univ Fed Rio Grande do Sul, Programa Posgrad Ciencias Saude Cardiol & Ciencia, Porto Alegre, RS, BrazilUniv Fed Rio Grande do Sul, Programa Posgrad Ciencias Saude Cardiol & Ciencia, Porto Alegre, RS, Brazil
Bertaso, Angela Gallina
;
Bertol, Daniela
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Rio Grande do Sul, Programa Posgrad Epidemiol, Porto Alegre, RS, BrazilUniv Fed Rio Grande do Sul, Programa Posgrad Ciencias Saude Cardiol & Ciencia, Porto Alegre, RS, Brazil
Bertol, Daniela
;
Duncan, Bruce Bartholow
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Rio Grande do Sul, Programa Posgrad Ciencias Saude Cardiol & Ciencia, Porto Alegre, RS, Brazil
Univ Fed Rio Grande do Sul, Programa Posgrad Epidemiol, Porto Alegre, RS, BrazilUniv Fed Rio Grande do Sul, Programa Posgrad Ciencias Saude Cardiol & Ciencia, Porto Alegre, RS, Brazil
Duncan, Bruce Bartholow
;
Foppa, Murilo
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Rio Grande do Sul, Programa Posgrad Ciencias Saude Cardiol & Ciencia, Porto Alegre, RS, Brazil
Univ Fed Rio Grande do Sul, Programa Posgrad Epidemiol, Porto Alegre, RS, BrazilUniv Fed Rio Grande do Sul, Programa Posgrad Ciencias Saude Cardiol & Ciencia, Porto Alegre, RS, Brazil
机构:
Emory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USAEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
He, Xiuxiu
;
Guo, Bang Jun
论文数: 0引用数: 0
h-index: 0
机构:
Emory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USA
Southern Med Univ, Jinling Hosp, Sch Clin Med 1, Dept Med Imaging, Nanjing 210002, Jiangsu, Peoples R ChinaEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Guo, Bang Jun
;
Lei, Yang
论文数: 0引用数: 0
h-index: 0
机构:
Emory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USAEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Lei, Yang
;
Wang, Tonghe
论文数: 0引用数: 0
h-index: 0
机构:
Emory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USAEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Wang, Tonghe
;
Fu, Yabo
论文数: 0引用数: 0
h-index: 0
机构:
Emory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USAEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Fu, Yabo
;
Curran, Walter J.
论文数: 0引用数: 0
h-index: 0
机构:
Emory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USAEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Curran, Walter J.
;
Zhang, Long Jiang
论文数: 0引用数: 0
h-index: 0
机构:
Southern Med Univ, Jinling Hosp, Sch Clin Med 1, Dept Med Imaging, Nanjing 210002, Jiangsu, Peoples R China
Nanjing Univ, Jinling Hosp, Dept Med Imaging, Sch Med, Nanjing 210002, Jiangsu, Peoples R ChinaEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Zhang, Long Jiang
;
Liu, Tian
论文数: 0引用数: 0
h-index: 0
机构:
Emory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USAEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Liu, Tian
;
Yang, Xiaofeng
论文数: 0引用数: 0
h-index: 0
机构:
Emory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USAEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
机构:
Univ Fed Rio Grande do Sul, Programa Posgrad Ciencias Saude Cardiol & Ciencia, Porto Alegre, RS, BrazilUniv Fed Rio Grande do Sul, Programa Posgrad Ciencias Saude Cardiol & Ciencia, Porto Alegre, RS, Brazil
Bertaso, Angela Gallina
;
Bertol, Daniela
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Rio Grande do Sul, Programa Posgrad Epidemiol, Porto Alegre, RS, BrazilUniv Fed Rio Grande do Sul, Programa Posgrad Ciencias Saude Cardiol & Ciencia, Porto Alegre, RS, Brazil
Bertol, Daniela
;
Duncan, Bruce Bartholow
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Rio Grande do Sul, Programa Posgrad Ciencias Saude Cardiol & Ciencia, Porto Alegre, RS, Brazil
Univ Fed Rio Grande do Sul, Programa Posgrad Epidemiol, Porto Alegre, RS, BrazilUniv Fed Rio Grande do Sul, Programa Posgrad Ciencias Saude Cardiol & Ciencia, Porto Alegre, RS, Brazil
Duncan, Bruce Bartholow
;
Foppa, Murilo
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Rio Grande do Sul, Programa Posgrad Ciencias Saude Cardiol & Ciencia, Porto Alegre, RS, Brazil
Univ Fed Rio Grande do Sul, Programa Posgrad Epidemiol, Porto Alegre, RS, BrazilUniv Fed Rio Grande do Sul, Programa Posgrad Ciencias Saude Cardiol & Ciencia, Porto Alegre, RS, Brazil
机构:
Emory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USAEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
He, Xiuxiu
;
Guo, Bang Jun
论文数: 0引用数: 0
h-index: 0
机构:
Emory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USA
Southern Med Univ, Jinling Hosp, Sch Clin Med 1, Dept Med Imaging, Nanjing 210002, Jiangsu, Peoples R ChinaEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Guo, Bang Jun
;
Lei, Yang
论文数: 0引用数: 0
h-index: 0
机构:
Emory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USAEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Lei, Yang
;
Wang, Tonghe
论文数: 0引用数: 0
h-index: 0
机构:
Emory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USAEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Wang, Tonghe
;
Fu, Yabo
论文数: 0引用数: 0
h-index: 0
机构:
Emory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USAEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Fu, Yabo
;
Curran, Walter J.
论文数: 0引用数: 0
h-index: 0
机构:
Emory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USAEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Curran, Walter J.
;
Zhang, Long Jiang
论文数: 0引用数: 0
h-index: 0
机构:
Southern Med Univ, Jinling Hosp, Sch Clin Med 1, Dept Med Imaging, Nanjing 210002, Jiangsu, Peoples R China
Nanjing Univ, Jinling Hosp, Dept Med Imaging, Sch Med, Nanjing 210002, Jiangsu, Peoples R ChinaEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Zhang, Long Jiang
;
Liu, Tian
论文数: 0引用数: 0
h-index: 0
机构:
Emory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USAEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Liu, Tian
;
Yang, Xiaofeng
论文数: 0引用数: 0
h-index: 0
机构:
Emory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA
Emory Univ, Winship Canc Inst, Atlanta, GA 30322 USAEmory Univ, Dept Radiat Oncol, Atlanta, GA 30322 USA